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Haploid genotype - rnh1delta rnh201delta

Genotype summary

Description
rnh1delta rnh201delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rnh1 (SPBC336.06c)ribonuclease H Rnh1rnh1deltadeletiondeletionNull
rnh201 (SPAC4G9.02)ribonuclease H2 complex subunit Rnh201rnh201deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0006321 - decreased protein localization to chromatin at stalled replication fork

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001742 - increased isochromosome formation

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FYPO:0007936 - increased number of DNA breakpoint junctions

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FYPO:0004822 - increased number of R-loops at rDNA

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FYPO:0006495 - increased number of R-loops at tRNA genes

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0001309 - increased viability in stationary phase

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FYPO:0005398 - normal frequency of double-strand break repair via homologous recombination

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FYPO:0004229 - normal growth during cellular response to ionizing radiation

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000472 - normal mating type switching

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0003481 - viable elongated vegetative cell, elongated upon mitotic entry

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