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Haploid genotype - rpb1-N494D(aa)

Genotype summary

Description
rpb1-N494D(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rpb1 (SPBC28F2.12)DNA-directed RNA polymerase II complex large subunit Rpb1rpb1-N494DN494Damino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007411 - abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during vegetative growth

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FYPO:0007409 - abnormal mRNA alternative polyadenylation

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FYPO:0007408 - abnormal protein localization to chromatin at polyadenylation site

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FYPO:0008037 - decreased rate of transcription elongation from RNA polymerase II promoter

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FYPO:0007407 - increased level of phosphate starvation gene mRNA during vegetative growth

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FYPO:0004066 - increased protein localization to chromatin at protein coding gene

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FYPO:0006614 - increased termination of RNA polymerase II transcription

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FYPO:0000084 - sensitive to 6-azauracil

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FYPO:0003670 - sensitive to mycophenolic acid

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