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Haploid genotype - rpb2-m203(N44Y aa)

Genotype summary

Description
rpb2-m203(N44Y aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rpb2 (SPAC23G3.01)DNA-directed RNA polymerase II complex subunit Rpb2rpb2-m203N44Yamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000187 - abnormal heterochromatin assembly by small RNA

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FYPO:0005843 - abolished histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0000273 - centromeric outer repeat transcripts absent

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FYPO:0004201 - decreased centromeric outer repeat transcript-derived siRNA level

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0007009 - decreased heterochromatin assembly by small RNA

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0000450 - decreased protein localization to centromere during vegetative growth

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FYPO:0010018 - increased histone H3-K36 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0002331 - increased histone H3-K4 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0000893 - increased histone H3-K9 acetylation at centromere during vegetative growth

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

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FYPO:0005866 - normal histone H3-K9 methylation at rDNA during vegetative growth

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FYPO:0002625 - normal protein localization to chromatin rDNA

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000091 - sensitive to thiabendazole

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