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Haploid genotype - sam1-3(L292S,R299H aa)

Genotype summary

Description
sam1-3(L292S,R299H aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
sam1 (SPBC14F5.05c)S-adenosylmethionine synthetasesam1-3L292S,R299Hamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0002955 - abnormal G0 to G1 transition

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0006698 - decreased cellular 5-phosphoribosyl diphosphate level

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FYPO:0006702 - decreased cellular adenine level

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FYPO:0006700 - decreased cellular CDP level

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FYPO:0006699 - decreased cellular hercynylcysteine sulfoxide level during vegetative growth

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FYPO:0006705 - decreased cellular pentose phosphate level

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FYPO:0006696 - decreased cellular S-adenosyl-L-homocysteine level during vegetative growth

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FYPO:0006695 - decreased cellular S-adenosyl-L-methionine level during vegetative growth

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FYPO:0006704 - decreased cellular sedoheptulose-7-phosphate level

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FYPO:0006703 - decreased cellular UDP level

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FYPO:0006701 - decreased cellular UMP level

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FYPO:0002367 - decreased histone H3-K4 dimethylation during vegetative growth

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FYPO:0002368 - decreased histone H3-K4 trimethylation during vegetative growth

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FYPO:0003865 - decreased protein level during G0

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0004555 - growth auxotrophic for choline

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FYPO:0006697 - increased cellular methionine level

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FYPO:0006518 - loss of viability in G0

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FYPO:0000717 - sensitive to actinomycin D

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FYPO:0002547 - sensitive to nicotinamide

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