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Haploid genotype - scs22delta scs2delta

Genotype summary

Description
scs22delta scs2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
scs22 (SPAC17C9.12)VAP family protein Scs22scs22deltadeletiondeletionNull
scs2 (SPBC16G5.05c)VAP family protein Scs2scs2deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0000230 - abnormal actomyosin contractile ring actin filament organization

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FYPO:0002872 - abnormal endoplasmic reticulum localization

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FYPO:0003444 - abnormal medial cortical node condensation

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FYPO:0001401 - abnormal protein localization to cell division site

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FYPO:0007449 - abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm

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FYPO:0002128 - abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth

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FYPO:0007447 - abolished reticulophagy during cellular response to endoplasmic reticulum stress

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FYPO:0000419 - decreased rate of cytokinesis

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FYPO:0004085 - decreased vegetative cell growth

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FYPO:0007263 - eisosomes present in decreased numbers

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FYPO:0005840 - incomplete, asymmetric septum

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FYPO:0006626 - increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane

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FYPO:0008330 - increased phosphatidylinositol-4-phosphate level in plasma membrane

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FYPO:0003337 - increased protein localization to septum

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FYPO:0000539 - increased protein secretion during vegetative growth

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FYPO:0000118 - multiseptate vegetative cell

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FYPO:0007441 - normal protein localization to endoplasmic reticulum-plasma membrane contact site

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FYPO:0002874 - premature protein localization to medial cortex during vegetative growth

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FYPO:0004730 - protein mislocalized to lateral cell cortex

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FYPO:0005264 - resistance to dithiothreitol

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FYPO:0000843 - sensitive to dithiothreitol

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FYPO:0002106 - viable stubby vegetative cell

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