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Haploid genotype - sfh1-13(E225D,K254E,P292Q aa)

Genotype summary

Description
sfh1-13(E225D,K254E,P292Q aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
sfh1 (SPCC16A11.14)RSC complex subunit Sfh1sfh1-13E225D,K254E,P292Qamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0003730 - abolished cell population growth on galactose carbon source

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FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0001162 - decreased cell population growth on raffinose carbon source

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FYPO:0001176 - decreased cell population growth on sucrose carbon source

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FYPO:0002842 - decreased protein localization to centromere outer repeat

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0004345 - decreased protein localization to chromatin at long terminal repeat

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FYPO:0008249 - decreased protein localization to chromatin at protein coding gene

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FYPO:0008035 - ectopic CENP-A containing chromatin assembly at pericentromeric heterochromatin

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FYPO:0005371 - increased linear minichromosome loss during vegetative growth

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FYPO:0008036 - increased nucleosome occupancy at CENP-A boundary

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0004380 - increased protein localization to pericentric heterochromatin during vegetative growth

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FYPO:0004922 - inviable elongated mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0000961 - normal growth on sorbitol

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FYPO:0000863 - normal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0004743 - normal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0008457 - normal nucleosome occupancy at long terminal repeat region

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0005079 - normal protein localization to chromatin at centromere central core

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FYPO:0005082 - normal protein localization to chromatin at long terminal repeat

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FYPO:0002389 - normal protein localization to heterochromatin at centromere outer repeat

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FYPO:0004579 - normal transposable element-derived small RNA level

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000785 - sensitive to formamide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0005889 - sensitive to sodium chloride

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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