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Haploid genotype - sgo2delta

Genotype summary

Description
sgo2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
sgo2 (SPAC15A10.15)centromeric adaptor, shugoshin Sgo2sgo2deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0004159 - abnormal homologous chromosome segregation

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FYPO:0005758 - abnormal regulation of mitotic DNA replication initiation from late origin

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FYPO:0004318 - abolished mitotic spindle assembly checkpoint

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FYPO:0006260 - abolished subtelomeric chromatin knob formation

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FYPO:0000251 - decreased cell population growth on galactose carbon source

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FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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FYPO:0000684 - decreased cell population growth on glycerol carbon source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0007562 - decreased cell population growth on serine nitrogen source

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FYPO:0010055 - decreased histone H2A-S121 phosphorylation at subtelomere during vegetative growth

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FYPO:0000460 - decreased mitotic centromeric sister chromatid cohesion

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FYPO:0003002 - decreased protein localization to centromere during mitotic metaphase

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FYPO:0002825 - decreased protein localization to mitotic spindle

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FYPO:0010051 - decreased protein localization to subtelomeric chromatin knob during vegetative growth

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FYPO:0005261 - increased cell population growth on galactose carbon source

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FYPO:0010056 - increased histone H3-K36 trimethylation at subtelomere during vegetative growth

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FYPO:0006263 - increased histone H3-K36 trimethylation during vegetative growth

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FYPO:0005225 - increased histone H3-K4 dimethylation during vegetative growth

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FYPO:0010053 - increased histone H4-K12 acetylation at subtelomeric chromatin knob during vegetative growth

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FYPO:0010052 - increased histone H4-K5 acetylation at subtelomeric chromatin knob during vegetative growth

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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FYPO:0004393 - lagging chromosomes during meiosis I

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0006518 - loss of viability in G0

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0005720 - normal mitotic metaphase chromosome recapture

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FYPO:0006428 - normal mitotic sister chromatid biorientation

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FYPO:0006645 - normal protein localization to mitotic spindle midzone during metaphase

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FYPO:0005602 - normal subtelomeric heterochromatin RNA level

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FYPO:0009036 - resistance to benzamidine

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FYPO:0000763 - resistance to cadmium

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001453 - resistance to ethanol

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FYPO:0001583 - resistance to lithium

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FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0005968 - resistance to sodium chloride

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FYPO:0000830 - resistance to vanadate

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0001457 - sensitive to tunicamycin

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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