Haploid genotype - sir2+(wild type)[Overexpression]
Genotype summary
Description
sir2+(wild type)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)
Allele summary
gene
Product
Allele name
Description
Type
Expression
sir2 (SPBC16D10.07c)
histone deacetylase, Sirtuin family, NAD-dependent Sir2
sir2+
wild type
wild_type
Overexpression
Annotation
Single locus phenotype
FYPO:0008413
-
increased establishment of chromatin silencing at centromere outer repeat region
References:
PMID:40063661
Genes:
sir2 (SPBC16D10.07c)
FYPO:0005940
-
increased replicative lifespan
References:
PMID:28139976
Genes:
sir2 (SPBC16D10.07c)