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Haploid genotype - sld3-10(E338G aa)

Genotype summary

Description
sld3-10(E338G aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
sld3 (SPAC24H6.06)DNA replication pre-initiation complex subunit Sld3sld3-10E338Gamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0006728 - abolished mitotic DNA replication initiation

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0001974 - increased number of cells with 1C DNA content

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0002060 - viable vegetative cell population

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