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Haploid genotype - snf21-36(V404A,E461K,S566L,I571V aa)

Genotype summary

Description
snf21-36(V404A,E461K,S566L,I571V aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
snf21 (SPAC1250.01)RSC-type complex ATPase Snf21snf21-36V404A,E461K,S566L,I571Vamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0000711 - decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation

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FYPO:0006857 - decreased histone H3-K37 methylation

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FYPO:0000460 - decreased mitotic centromeric sister chromatid cohesion

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0005948 - decreased protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth

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FYPO:0007209 - decreased sister chromatid cohesion along chromosome arms during mitotic interphase

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FYPO:0006355 - delayed onset of transcription during glucose starvation

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FYPO:0008035 - ectopic CENP-A containing chromatin assembly at pericentromeric heterochromatin

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0006842 - normal spatial extent of CENP-A containing nucleosome assembly

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FYPO:0000091 - sensitive to thiabendazole

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