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Haploid genotype - spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)

Genotype summary

Description
spc7-12E(T77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552E aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
spc7 (SPCC1020.02)outer kinetochore KNL network protein, KNL-1 family member, blinkin, Spc7spc7-12ET77E,S221E,T257E,T338E,T366E,T395E,T413E,T422E,T453E,T507E,T529E,T552Eamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0007174 - abnormal protein localization to kinetochore during mitotic interphase

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FYPO:0001268 - abnormal protein localization to kinetochore during vegetative growth

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0008165 - decreased protein localization to kinetochore during mitotic prometaphase

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FYPO:0005780 - decreased response to mitotic spindle assembly checkpoint signaling

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FYPO:0005232 - normal protein complex binding

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FYPO:0000091 - sensitive to thiabendazole

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