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Haploid genotype - spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)

Genotype summary

Description
spc7-12TA(T77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
spc7 (SPCC1020.02)outer kinetochore KNL network protein, KNL-1 family member, blinkin, Spc7spc7-12TAT77A,S221A,T257A,T338A,T366A,T395A,T413A,T422A,T453A,T507A,T529A,T552Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0003591 - abnormal protein complex binding

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FYPO:0004763 - abolished protein localization to kinetochore during meiosis I

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FYPO:0008166 - abolished protein localization to kinetochore during mitotic prometaphase

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FYPO:0002678 - abolished protein phosphorylation

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0005781 - decreased duration of mitotic spindle assembly checkpoint

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FYPO:0006423 - decreased meiotic sister chromatid cohesion at centromere during meiosis I

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FYPO:0004212 - decreased protein localization to kinetochore during meiosis I

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FYPO:0005300 - decreased protein localization to kinetochore during mitotic spindle assembly checkpoint signaling

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0005780 - decreased response to mitotic spindle assembly checkpoint signaling

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001571 - increased protein-protein interaction

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FYPO:0005042 - normal protein localization to kinetochore

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FYPO:0000091 - sensitive to thiabendazole

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