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Haploid genotype - spt5-degron[Knockdown]

Genotype summary

Description
spt5-degron[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
spt5 (SPAC23C4.19)DSIF transcription elongation factor complex subunit Spt5spt5-degronspt5-degronfusion_or_chimeraKnockdown

Annotation

Single locus phenotype

FYPO:0000189 - abnormal mRNA splicing, via spliceosome

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FYPO:0006020 - abnormal protein distribution along RNA polymerase II-transcribed genes

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FYPO:0004126 - abolished histone H3-K4 trimethylation during vegetative growth

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FYPO:0004067 - decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth

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FYPO:0004161 - decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0005229 - decreased transcription from RNA polymerase II promoter during vegetative growth

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0005061 - normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth

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