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Haploid genotype - spt6-1(856-919 Δaa)

Genotype summary

Description
spt6-1(856-919 Δaa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
spt6 (SPAC1F7.01c)histone H3-H4 chaperone Spt6spt6-1856-919partial_amino_acid_deletionNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000886 - abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0000864 - abnormal histone H3-K9 trimethylation at centromere during vegetative growth

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FYPO:0000865 - abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth

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FYPO:0000885 - abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0000854 - abnormal nucleosome positioning in euchromatin

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FYPO:0002919 - abolished histone H3-K36 methylation during vegetative growth

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FYPO:0002917 - abolished histone H3-K4 methylation during vegetative growth

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FYPO:0002834 - decreased chromatin silencing at centromere

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FYPO:0003216 - decreased chromatin silencing at rDNA

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0000450 - decreased protein localization to centromere during vegetative growth

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FYPO:0002910 - decreased protein localization to chromatin at transcribed regions during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0002906 - increased antisense primary transcript splicing

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0000220 - increased centromeric outer repeat transcript level

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FYPO:0000893 - increased histone H3-K9 acetylation at centromere during vegetative growth

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FYPO:0000879 - increased histone H3-K9 trimethylation during vegetative growth

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FYPO:0002914 - increased intergenic transcription

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FYPO:0000786 - increased plasmid loss

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FYPO:0002923 - normal histone H2B-K119 ubiquitination during vegetative growth

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FYPO:0000862 - normal histone H3-K9 dimethylation at centromere during vegetative growth

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FYPO:0000863 - normal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0000858 - normal nucleosome positioning in heterochromatin

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000785 - sensitive to formamide

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FYPO:0000091 - sensitive to thiabendazole

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