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Haploid genotype - srs2delta

Genotype summary

Description
srs2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
srs2 (SPAC4H3.05)ATP-dependent DNA helicase, UvrD subfamilysrs2deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000059 - abnormal mitotic cell cycle

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FYPO:0003912 - decreased double-strand break repair via homologous recombination

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FYPO:0006494 - decreased rDNA copy number during vegetative growth

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FYPO:0001122 - elongated vegetative cell

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FYPO:0003938 - increased cell population growth during glucose starvation

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FYPO:0009052 - increased cell population growth on glutamate nitrogen source

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0009093 - increased cell population growth on lysine and serine nitrogen source

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FYPO:0009028 - increased cell population growth on proline nitrogen source

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FYPO:0009074 - increased cell population growth on serine nitrogen source

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FYPO:0009096 - increased cell population growth on xylose carbon source

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0000167 - increased DNA recombination at mitotic DNA replication fork barriers

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FYPO:0007006 - increased DNA recombination downstream of mitotic DNA replication fork barriers

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FYPO:0005361 - increased level of large-Y replication intermediates

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FYPO:0000473 - increased mitotic recombination

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FYPO:0001974 - increased number of cells with 1C DNA content

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0001927 - normal cell cycle regulation during cellular response to ionizing radiation

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0005353 - normal replication fork arrest at RTS1 barrier

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FYPO:0003530 - normal S-phase DNA damage checkpoint

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FYPO:0005354 - normal site-specific DNA replication termination at RTS1 barrier

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0009030 - resistance to amitrole

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FYPO:0000763 - resistance to cadmium

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0001103 - resistance to hydrogen peroxide

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FYPO:0009070 - resistance to itraconazole

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0001034 - resistance to tunicamycin

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FYPO:0000830 - resistance to vanadate

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0009067 - sensitive to amorolfine

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0001701 - sensitive to bortezomib

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FYPO:0001501 - sensitive to brefeldin A

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0009080 - sensitive to calcofluor and sodium dodecyl sulfate

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0002701 - sensitive to torin1

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0001492 - viable elongated vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002197 - viable vegetative cell with abnormal cell shape

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FYPO:0002104 - viable vegetative cell with normal cell shape

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