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Haploid genotype - swi1delta

Genotype summary

Description
swi1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
swi1 (SPBC216.06c)replication fork protection complex subunit Swi1swi1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0005778 - abnormal chromosome morphology during cellular response to acetaldehyde

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FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0002603 - abolished histone H2A phosphorylation at mating type locus during mitotic S phase

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FYPO:0001424 - abolished protein localization to nucleus during vegetative growth

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FYPO:0001054 - cut, elongated cell

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FYPO:0003743 - decreased cell population growth during glucose starvation

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FYPO:0003092 - decreased chromatin binding at mating-type region replication fork barrier

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0000658 - decreased DNA binding

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0005011 - decreased histone H4 acetylation during vegetative growth

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FYPO:0000460 - decreased mitotic centromeric sister chromatid cohesion

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0003950 - decreased protein localization to chromatin at replication origin

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FYPO:0002909 - decreased protein localization to chromatin during vegetative growth

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001128 - decreased septation index

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004003 - delayed onset of replication fork processing

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FYPO:0001122 - elongated vegetative cell

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FYPO:0000167 - increased DNA recombination at mitotic DNA replication fork barriers

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0005788 - increased gene conversion during vegetative growth

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FYPO:0002607 - increased histone H2A phosphorylation at centromeric tDNA during mitotic S phase

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FYPO:0002605 - increased histone H2A phosphorylation at rDNA during mitotic G2 phase

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FYPO:0002606 - increased histone H2A phosphorylation at rDNA during mitotic S phase

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FYPO:0001742 - increased isochromosome formation

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FYPO:0000455 - increased number of double-strand break sites during vegetative growth

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0001249 - increased origin firing efficiency

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FYPO:0000847 - increased protein degradation during vegetative growth

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0003087 - normal chromatin binding at mating-type region replication fork barrier

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FYPO:0004742 - normal chromatin silencing at centromere outer repeat

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0007249 - normal level of X-shaped replication intermediates

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FYPO:0002800 - normal protein degradation during vegetative growth

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0003530 - normal S-phase DNA damage checkpoint

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0002693 - resistance to diamide

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000725 - resistance to methyl methanesulfonate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0005775 - sensitive to acetaldehyde

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000102 - sensitive to cisplatin

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0007330 - sensitive to formaldehyde

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0002546 - sensitive to trichostatin A

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0001492 - viable elongated vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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