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Haploid genotype - swi3delta

Genotype summary

Description
swi3delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
swi3 (SPBC30D10.04)replication fork protection complex subunit Swi3swi3deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000427 - abnormal G1 to G0 transition

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FYPO:0006521 - abnormal mitotic sister chromatid cohesion

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FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0002603 - abolished histone H2A phosphorylation at mating type locus during mitotic S phase

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FYPO:0006677 - decreased DNA binding at double-strand break

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FYPO:0003352 - decreased DNA double-strand break formation at mating-type locus

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0000470 - decreased mating type switching

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FYPO:0000460 - decreased mitotic centromeric sister chromatid cohesion

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002909 - decreased protein localization to chromatin during vegetative growth

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FYPO:0004056 - decreased protein localization to nucleus, with protein mislocalized to cytoplasm

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001122 - elongated vegetative cell

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FYPO:0003938 - increased cell population growth during glucose starvation

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FYPO:0005261 - increased cell population growth on galactose carbon source

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FYPO:0009101 - increased cell population growth on glycerol and galactose carbon source

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0009093 - increased cell population growth on lysine and serine nitrogen source

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FYPO:0009028 - increased cell population growth on proline nitrogen source

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FYPO:0009074 - increased cell population growth on serine nitrogen source

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FYPO:0009096 - increased cell population growth on xylose carbon source

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FYPO:0005296 - increased number of Rad52 foci during mitotic S phase

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0001908 - increased pre-mRNA level

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FYPO:0004557 - increased vegetative cell population growth

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FYPO:0006518 - loss of viability in G0

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0007249 - normal level of X-shaped replication intermediates

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FYPO:0002800 - normal protein degradation during vegetative growth

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0009036 - resistance to benzamidine

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FYPO:0000763 - resistance to cadmium

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000725 - resistance to methyl methanesulfonate

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FYPO:0001034 - resistance to tunicamycin

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0000084 - sensitive to 6-azauracil

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FYPO:0001701 - sensitive to bortezomib

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000799 - sensitive to diamide

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000785 - sensitive to formamide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0006836 - sensitive to magnesium chloride

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0003656 - sensitive to vanadate

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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