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Haploid genotype - tdp1delta

Genotype summary

Description
tdp1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
tdp1 (SPCP31B10.05)tyrosyl-DNA phosphodiesterase Tdp1tdp1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000262 - abnormal cellular response to reactive oxygen species during G0

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FYPO:0007229 - abolished 3'-deoxyribose phosphate lyase activity

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FYPO:0004710 - increased number of Rad52 foci during G0 to G1 transition

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FYPO:0000238 - inviable cell upon G0 to G1 transition

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0005622 - normal topoisomerase-DNA adduct level

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003384 - sensitive to chromium

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0001719 - sensitive to lithium

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0000108 - sensitive to menadione

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0001457 - sensitive to tunicamycin

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FYPO:0003656 - sensitive to vanadate

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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