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Haploid genotype - top1-(unknown) top2-(unknown)

Genotype summary

Description
top1-(unknown) top2-(unknown)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
top1 (SPBC1703.14c)DNA topoisomerase Itop1-unknownunknownNot assayed or wild type
top2 (SPBC1A4.03c)DNA topoisomerase IItop2-unknownunknownNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0001352 - abnormal chromatin organization during vegetative growth

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FYPO:0000848 - abnormal chromosome morphology during vegetative growth

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FYPO:0004506 - abnormal nucleolar chromatin organization resulting in peripheral chromatin distribution

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0003689 - abolished protein localization to nucleolus, with protein mislocalized to cytoplasm

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