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Haploid genotype - top1delta

Genotype summary

Description
top1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
top1 (SPBC1703.14c)DNA topoisomerase Itop1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0005951 - decreased nucleosome occupancy at highly transcribed RNA polymerase II genes

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0003938 - increased cell population growth during glucose starvation

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FYPO:0009072 - increased cell population growth on lysine nitrogen source

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FYPO:0004066 - increased protein localization to chromatin at protein coding gene

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FYPO:0004032 - increased protein localization to chromatin at rDNA

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FYPO:0004571 - increased RNA level during cellular response to hydrogen peroxide

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FYPO:0001309 - increased viability in stationary phase

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0008245 - normal protein localization to chromatin at gene promoter region

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FYPO:0004422 - normal protein phosphorylation

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FYPO:0009031 - resistance to bleomycin

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FYPO:0000763 - resistance to cadmium

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FYPO:0001032 - resistance to camptothecin

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0002693 - resistance to diamide

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FYPO:0001103 - resistance to hydrogen peroxide

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0005969 - resistance to magnesium chloride

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0000830 - resistance to vanadate

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FYPO:0000096 - sensitive to cadmium

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0000785 - sensitive to formamide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0001491 - viable vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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