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Haploid genotype - tpz1-W498R,I501R(aa)[Knockdown]

Genotype summary

Description
tpz1-W498R,I501R(aa)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
tpz1 (SPAC6F6.16c)shelterin complex subunit Tpz1tpz1-W498R,I501RW498R,I501Ramino_acid_mutationKnockdown

Annotation

Single locus phenotype

FYPO:0000705 - abolished protein-protein interaction

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0003803 - decreased protein localization to telomere

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FYPO:0002019 - elongated telomeres during vegetative growth

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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