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Haploid genotype - ubp12-NES ubp15-NES ubp16delta ubp2delta

Genotype summary

Description
ubp12-NES ubp15-NES ubp16delta ubp2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ubp12 (SPCC1494.05c)CSN-associated deubiquitinating enzyme Ubp12ubp12-NESubp12-NESfusion_or_chimeraNot assayed or wild type
ubp15 (SPBC713.02c)ubiquitin C-terminal hydrolase Ubp15ubp15-NESubp15-NESfusion_or_chimeraNot assayed or wild type
ubp16 (SPCC1682.12c)ubiquitin C-terminal hydrolase Ubp16ubp16deltadeletiondeletionNull
ubp2 (SPAC328.06)ubiquitin C-terminal hydrolase Ubp2ubp2deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0005323 - abnormal error-free translesion synthesis

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FYPO:0005679 - decreased protein deubiquitination following cellular response to hydroxyurea during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000614 - increased duration of mitotic S phase

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FYPO:0004436 - increased error-prone translesion synthesis

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FYPO:0002774 - increased level of ubiquitinated protein in cell during vegetative growth

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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