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Haploid genotype - wis1-DD(S469D,T473D aa)[Overexpression]

Genotype summary

Description
wis1-DD(S469D,T473D aa)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
wis1 (SPBC409.07c)MAP kinase kinase Wis1wis1-DDS469D,T473Damino_acid_mutationOverexpression

Annotation

Single locus phenotype

FYPO:0002678 - abolished protein phosphorylation

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0003571 - decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0003075 - normal protein kinase activity

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