id: gomodel:69729a3800007453
title: protein import into mitochondrial matrix (GO:0030150)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-04-16'
activities:
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  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - SGD:S000000004
      provenances:
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        date: '2026-04-05'
        provided_by:
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      date: '2026-04-05'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPCC550.06c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0044183
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000080672
      - SGD:S000005546
      - RGD:2844
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        date: '2026-02-15'
        provided_by:
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      date: '2026-02-15'
      provided_by:
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    term: GO:0005759
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000250
      reference: GO_REF:0000024
      with_objects:
      - UniProtKB:P38910
      provenances:
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        date: '2026-02-15'
        provided_by:
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    provenances:
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      date: '2026-02-15'
      provided_by:
      - http://www.pombase.org
    term: GO:0030150
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
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      date: '2026-02-15'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:69729a3800007453/698e557b00000799
- id: gomodel:69729a3800007453/6994852c00000297
  enabled_by:
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    evidence:
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      reference: GO_REF:0000002
      with_objects:
      - InterPro:IPR000740
      provenances:
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        date: '2026-02-18'
        provided_by:
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    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000478264
      - SGD:S000005758
      - UniProtKB:P09372
      provenances:
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    provenances:
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      date: '2026-02-18'
      provided_by:
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    term: PomBase:SPBC3B9.19
    part_of:
    - type: PartOfProteinComplexAssociation
      evidence:
      - term: ECO:0000266
        reference: GO_REF:0000024
        with_objects:
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        provenances:
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          date: '2026-02-25'
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      provenances:
      - contributor:
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        date: '2026-02-25'
        provided_by:
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      term: GO:0001405
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0000774
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0001405
      provenances:
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        date: '2026-02-18'
        provided_by:
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    provenances:
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      date: '2026-02-18'
      provided_by:
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    term: GO:0005759
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - SGD:S000005758
      provenances:
      - contributor:
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        date: '2026-02-18'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000478265
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      provenances:
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        date: '2026-02-18'
        provided_by:
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    provenances:
    - contributor:
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      date: '2026-02-18'
      provided_by:
      - http://www.pombase.org
    term: GO:0030150
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000501
      reference: GO_REF:0000002
      with_objects:
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      provenances:
      - contributor:
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        date: '2026-02-18'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000478264
      - SGD:S000005758
      - UniProtKB:P09372
      provenances:
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        date: '2026-02-18'
        provided_by:
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    provenances:
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      date: '2026-02-18'
      provided_by:
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    predicate: RO:0002629
    downstream_activity: gomodel:69729a3800007453/6994852c00000305
- id: gomodel:69729a3800007453/698e557b00000756
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      reference: GO_REF:0000033
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      - PANTHER:PTN000211184
      - SGD:S000000562
      - UniProtKB:Q389Z4
      - MGI:MGI:1354165
      - SGD:S000001617
      - RGD:621518
      provenances:
      - contributor:
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        date: '2026-02-15'
        provided_by:
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    - term: ECO:0000501
      reference: GO_REF:0000003
      with_objects:
      - EC:3.4.24.59
      provenances:
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        date: '2026-02-15'
        provided_by:
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    provenances:
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      date: '2026-02-15'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC1F3.10c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004222
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000250
      reference: GO_REF:0000024
      with_objects:
      - UniProtKB:P35999
      provenances:
      - contributor:
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        date: '2026-02-15'
        provided_by:
        - http://www.pombase.org
    provenances:
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      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-15'
      provided_by:
      - http://www.pombase.org
    term: GO:0005759
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - SGD:S000001617
      provenances:
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        date: '2026-02-15'
        provided_by:
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    provenances:
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      date: '2026-02-15'
      provided_by:
      - http://www.pombase.org
    term: GO:0034982
  molecular_associations:
  - type: MoleculeAssociation
    evidence: []
    provenances:
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      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001097
  - type: MoleculeAssociation
    evidence: []
    provenances:
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001061
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001060
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001096
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001095
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001094
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001065
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001093
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      provided_by:
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001092
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001064
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001059
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001091
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    molecule: gomodel:69729a3800007453/698e557b00001098
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    molecule: gomodel:69729a3800007453/698e557b00001058
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    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001062
  causal_associations:
  - type: CausalAssociation
    evidence:
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      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000211184
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        provided_by:
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    - term: ECO:0000501
      reference: GO_REF:0000003
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        provided_by:
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    - term: ECO:0000318
      reference: GO_REF:0000033
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    - term: ECO:0000501
      reference: GO_REF:0000003
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    predicate: RO:0002413
    downstream_activity: gomodel:69729a3800007453/698e557b00001022
  - type: CausalAssociation
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    predicate: RO:0002413
    downstream_activity: gomodel:69729a3800007453/698e557b00001022
- id: gomodel:69729a3800007453/69729a3800007537
  enabled_by:
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    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
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        date: '2026-02-18'
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    provenances:
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      date: '2026-02-18'
      provided_by:
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    term: PomBase:SPBC27B12.10c
    part_of:
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      evidence: []
      provenances:
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        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
      term: GO:0140596
    - type: PartOfProteinComplexAssociation
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      - term: ECO:0000266
        reference: GO_REF:0000024
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      term: GO:0140596
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003674
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
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      provided_by:
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    term: GO:0005741
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      reference: GO_REF:0000002
      with_objects:
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    - term: ECO:0000250
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    - term: ECO:0000318
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      provided_by:
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    term: GO:0030150
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    predicate: RO:0012009
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- id: gomodel:69729a3800007453/69729a3800007642
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    - term: ECO:0000266
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    - term: ECO:0000266
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      provided_by:
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    term: PomBase:SPBC17A3.01c
    part_of:
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      term: GO:0005744
  molecular_function:
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    term: GO:0030943
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    term: GO:0005759
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    - term: ECO:0000318
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    term: GO:0030150
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    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001102
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001103
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001051
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001099
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001104
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001052
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001105
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001053
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001054
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001100
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69729a3800007453/698e557b00001101
molecules:
- id: gomodel:69729a3800007453/698e557b00001102
  term: PomBase:SPAC24C9.06c
- id: gomodel:69729a3800007453/698e557b00001097
  term: PomBase:SPBC9B6.04c
- id: gomodel:69729a3800007453/698e557b00001061
  term: PomBase:SPAC1556.02c
- id: gomodel:69729a3800007453/698e557b00001060
  term: PomBase:SPCC306.08c
- id: gomodel:69729a3800007453/698e557b00001096
  term: PomBase:SPAC2F3.04c
- id: gomodel:69729a3800007453/698e557b00001103
  term: PomBase:SPBP4H10.15
- id: gomodel:69729a3800007453/698e557b00001051
  term: PomBase:SPBC1604.13c
- id: gomodel:69729a3800007453/698e557b00001099
  term: PomBase:SPBC3H7.03c
- id: gomodel:69729a3800007453/698e557b00001104
  term: PomBase:SPAC17G8.06c
- id: gomodel:69729a3800007453/698e557b00001095
  term: PomBase:SPBC11B10.04c
- id: gomodel:69729a3800007453/698e557b00001052
  term: PomBase:SPBC2F12.10
- id: gomodel:69729a3800007453/698e557b00001094
  term: PomBase:SPBC839.09c
- id: gomodel:69729a3800007453/698e557b00001105
  term: PomBase:SPAC11G7.03
- id: gomodel:69729a3800007453/698e557b00001065
  term: PomBase:SPBC56F2.12
- id: gomodel:69729a3800007453/698e557b00001053
  term: PomBase:SPAC14C4.14
- id: gomodel:69729a3800007453/698e557b00001093
  term: PomBase:SPCC306.08c
- id: gomodel:69729a3800007453/698e557b00001054
  term: PomBase:SPAC222.12c
- id: gomodel:69729a3800007453/698e557b00001092
  term: PomBase:SPBP23A10.16
- id: gomodel:69729a3800007453/698e557b00001039
  term: PomBase:SPBC1718.06
- id: gomodel:69729a3800007453/698e557b00001064
  term: PomBase:SPBC902.05c
- id: gomodel:69729a3800007453/698e557b00001055
  term: PomBase:SPBC2F12.10
- id: gomodel:69729a3800007453/698e557b00001059
  term: PomBase:SPCC4G3.14
- id: gomodel:69729a3800007453/698e557b00001100
  term: PomBase:SPBC776.15c
- id: gomodel:69729a3800007453/698e557b00001091
  term: PomBase:SPBC16H5.06
- id: gomodel:69729a3800007453/698e557b00001098
  term: PomBase:SPAC22H12.03
- id: gomodel:69729a3800007453/698e557b00001058
  term: PomBase:SPAC1296.02
- id: gomodel:69729a3800007453/698e557b00001101
  term: PomBase:SPAC4G9.10
- id: gomodel:69729a3800007453/698e557b00001062
  term: PomBase:SPBC530.13
objects:
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0016504
  label: peptidase activator activity
  type: gocam:Object
- id: PomBase:SPBC18E5.12c
  label: mas2 Spom
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0034982
  label: mitochondrial protein processing
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: GO:0017087
  label: mitochondrial processing peptidase complex
  type: gocam:Object
- id: GO:0043171
  label: peptide catabolic process
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0008320
  label: transmembrane protein transporter activity
  type: gocam:Object
- id: PomBase:SPBC27B12.13
  label: tom40 Spom
  type: gocam:Object
- id: GO:0030150
  label: protein import into mitochondrial matrix
  type: gocam:Object
- id: GO:0005741
  label: mitochondrial outer membrane
  type: gocam:Object
- id: GO:0140596
  label: TOM complex
  type: gocam:Object
- id: GO:0003674
  label: molecular_function
  type: gocam:Object
- id: PomBase:SPBC19G7.19
  label: tom5 Spom
  type: gocam:Object
- id: PomBase:SPAC17H9.16
  label: tom22 Spom
  type: gocam:Object
- id: PomBase:SPAC823.17
  label: tom6 Spom
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC27B12.10c
  label: tom7 Spom
  type: gocam:Object
- id: PomBase:SPAC3A12.16c
  label: tim17 Spom
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: GO:0030943
  label: mitochondrion targeting sequence binding
  type: gocam:Object
- id: PomBase:SPBC17A3.01c
  label: tim50 Spom
  type: gocam:Object
- id: GO:0005744
  label: TIM23 mitochondrial import inner membrane translocase complex
  type: gocam:Object
- id: GO:0009003
  label: signal peptidase activity
  type: gocam:Object
- id: PomBase:SPBP23A10.15c
  label: mas1 Spom
  type: gocam:Object
- id: GO:0004222
  label: metalloendopeptidase activity
  type: gocam:Object
- id: PomBase:SPAC1F3.10c
  label: oct1 Spom
  type: gocam:Object
- id: GO:0070006
  label: metalloaminopeptidase activity
  type: gocam:Object
- id: PomBase:SPAC12B10.05
  label: icp55 Spom
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: GO:0044183
  label: protein folding chaperone
  type: gocam:Object
- id: PomBase:SPCC550.06c
  label: hsp10 Spom
  type: gocam:Object
- id: GO:0140662
  label: ATP-dependent protein folding chaperone
  type: gocam:Object
- id: PomBase:SPAC12G12.04
  label: mcp60 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC119.17
  label: cym1 Spom
  type: gocam:Object
- id: GO:0004252
  label: serine-type endopeptidase activity
  type: gocam:Object
- id: PomBase:SPBC13E7.11
  label: rbd1 Spom
  type: gocam:Object
- id: PomBase:SPBC1718.06
  label: msp1 Spom
  type: gocam:Object
- id: PomBase:SPBC1604.13c
  label: mrpl32 Spom
  type: gocam:Object
- id: PomBase:SPBC2F12.10
  label: mrpl35 Spom
  type: gocam:Object
- id: PomBase:SPAC14C4.14
  label: atp1 Spom
  type: gocam:Object
- id: PomBase:SPAC222.12c
  label: atp2 Spom
  type: gocam:Object
- id: PomBase:SPAC1296.02
  label: cox4 Spom
  type: gocam:Object
- id: PomBase:SPCC4G3.14
  label: mdj1 Spom
  type: gocam:Object
- id: PomBase:SPCC306.08c
  label: mdh1 Spom
  type: gocam:Object
- id: PomBase:SPAC1556.02c
  label: sdh1 Spom
  type: gocam:Object
- id: PomBase:SPBC530.13
  label: lsc1 Spom
  type: gocam:Object
- id: PomBase:SPBC902.05c
  label: idh2 Spom
  type: gocam:Object
- id: PomBase:SPBC56F2.12
  label: ilv5 Spom
  type: gocam:Object
- id: PomBase:SPBC16H5.06
  label: rip1 Spom
  type: gocam:Object
- id: PomBase:SPBP23A10.16
  label: sdh4 Spom
  type: gocam:Object
- id: PomBase:SPBC839.09c
  label: mrp21 Spom
  type: gocam:Object
- id: PomBase:SPBC11B10.04c
  label: mrps28 Spom
  type: gocam:Object
- id: PomBase:SPAC2F3.04c
  label: rim1 Spom
  type: gocam:Object
- id: PomBase:SPBC9B6.04c
  label: tuf1 Spom
  type: gocam:Object
- id: PomBase:SPAC22H12.03
  label: pah2 Spom
  type: gocam:Object
- id: PomBase:SPBC3H7.03c
  label: kgd1 Spom
  type: gocam:Object
- id: PomBase:SPBC776.15c
  label: kgd2 Spom
  type: gocam:Object
- id: PomBase:SPAC4G9.10
  label: arg3 Spom
  type: gocam:Object
- id: PomBase:SPAC24C9.06c
  label: aco1 Spom
  type: gocam:Object
- id: PomBase:SPBP4H10.15
  label: aco2 Spom
  type: gocam:Object
- id: PomBase:SPAC17G8.06c
  label: ilv3 Spom
  type: gocam:Object
- id: PomBase:SPAC11G7.03
  label: idh1 Spom
  type: gocam:Object
- id: PomBase:SPAC6F12.07
  label: tom20 Spom
  type: gocam:Object
- id: GO:0000774
  label: adenyl-nucleotide exchange factor activity
  type: gocam:Object
- id: PomBase:SPBC3B9.19
  label: mge1 Spom
  type: gocam:Object
- id: GO:0016887
  label: ATP hydrolysis activity
  type: gocam:Object
- id: PomBase:SPAC664.11
  label: ssc1 Spom
  type: gocam:Object
- id: GO:0001405
  label: PAM complex, Tim23 associated import motor
  type: gocam:Object
- id: PomBase:SPAC167.04
  label: pam17 Spom
  type: gocam:Object
- id: GO:0001671
  label: ATPase activator activity
  type: gocam:Object
- id: PomBase:SPAC824.06
  label: pam18 Spom
  type: gocam:Object
- id: GO:0140388
  label: protein translocation chaperone activity
  type: gocam:Object
- id: PomBase:SPBC713.10
  label: pam16 Spom
  type: gocam:Object
- id: GO:0140378
  label: protein complex scaffold activity
  type: gocam:Object
- id: PomBase:SPBC14C8.02
  label: tim44 Spom
  type: gocam:Object
- id: PomBase:SPCC16A11.09c
  label: tim23 Spom
  type: gocam:Object
- id: PomBase:SPAC24H6.02c
  label: zim17 Spom
  type: gocam:Object
- id: PomBase:SPBC27.06c
  label: mgr2 Spom
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-04-16'
  provided_by:
  - http://www.pombase.org
