id: gomodel:69a0c46f00003187
title: alpha helical protein insertion into mitochondrial outer membrane (GO:7770059)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-04-15'
activities:
- id: gomodel:69a0c46f00003187/69a0c46f00003210
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-04-15'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC6B12.12
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005048
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN002340064
      - RGD:1303049
      - SGD:S000005065
      - SGD:S000001159
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-11'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-11'
      provided_by:
      - http://www.pombase.org
    term: GO:0005741
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000304
      reference: PMID:21825074
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-15'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-04-15'
      provided_by:
      - http://www.pombase.org
    term: GO:7770059
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-11'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-11'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002304
    downstream_activity: gomodel:69a0c46f00003187/69a0c46f00003201
- id: gomodel:69a0c46f00003187/69a0c46f00003201
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:33138913
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-11'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-11'
      provided_by:
      - http://www.pombase.org
    term: GO:0140595
    has_part:
    - type: ProteinComplexHasPartAssociation
      evidence:
      - term: ECO:0000304
        reference: PMID:33138913
        provenances:
        - contributor:
          - https://orcid.org/0000-0001-6330-7526
          date: '2026-04-15'
          provided_by:
          - http://www.pombase.org
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-15'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC409.23
    - type: ProteinComplexHasPartAssociation
      evidence:
      - term: ECO:0000304
        reference: PMID:33138913
        provenances:
        - contributor:
          - https://orcid.org/0000-0001-6330-7526
          date: '2026-04-15'
          provided_by:
          - http://www.pombase.org
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-15'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC713.08
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0032977
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0140595
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-11'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-11'
      provided_by:
      - http://www.pombase.org
    term: GO:0005741
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:33138913
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-15'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-11'
      provided_by:
      - http://www.pombase.org
    term: GO:7770059
  molecular_associations:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000582
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000576
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000560
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0005647
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000555
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000578
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000562
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69a0c46f00003220
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:33138913
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-15'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-04-15'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69a0c46f00003219
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000580
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000564
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000566
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000570
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000568
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000574
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000266
      reference: PMID:32348752
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69a0c46f00003187/69c59f8a00000572
molecules:
- id: gomodel:69a0c46f00003187/69c59f8a00000582
  term: PomBase:SPBC11G11.01
- id: gomodel:69a0c46f00003187/69c59f8a00000576
  term: PomBase:SPAC19A8.14
- id: gomodel:69a0c46f00003187/69c59f8a00000560
  term: PomBase:SPBC19G7.19
- id: gomodel:69a0c46f00003187/69c59f8a00000555
  term: PomBase:SPAC6F12.07
- id: gomodel:69a0c46f00003187/69c59f8a00000578
  term: PomBase:SPAC1A6.10
- id: gomodel:69a0c46f00003187/69c59f8a00000562
  term: PomBase:SPAC823.17
- id: gomodel:69a0c46f00003187/69a0c46f00003220
  term: PomBase:SPAC6B12.12
- id: gomodel:69a0c46f00003187/69a0c46f00003219
  term: PomBase:SPAC14C4.01c
- id: gomodel:69a0c46f00003187/69c59f8a00000580
  term: PomBase:SPCC320.04c
- id: gomodel:69a0c46f00003187/69c59f8a00000564
  term: PomBase:SPBC27B12.10c
- id: gomodel:69a0c46f00003187/69c59f8a00000566
  term: PomBase:SPAC1B2.02c
- id: gomodel:69a0c46f00003187/69c59f8a00000570
  term: PomBase:SPBC11C11.06c
- id: gomodel:69a0c46f00003187/69c59f8a00000568
  term: PomBase:SPBC1706.03
- id: gomodel:69a0c46f00003187/69c59f8a00000574
  term: PomBase:SPBC1718.06
- id: gomodel:69a0c46f00003187/69c59f8a00000572
  term: PomBase:SPAC29A4.17c
objects:
- id: GO:0032977
  label: membrane insertase activity
  type: gocam:Object
- id: GO:0140595
  label: MIM complex
  type: gocam:Object
- id: GO:7770059
  label: alpha helical protein insertion into mitochondrial outer membrane
  type: gocam:Object
- id: GO:0005741
  label: mitochondrial outer membrane
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC713.08
  label: mim1 Spom
  type: gocam:Object
- id: PomBase:SPBC409.23
  label: mim2 Spom
  type: gocam:Object
- id: GO:0005048
  label: signal sequence binding
  type: gocam:Object
- id: PomBase:SPAC6B12.12
  label: tom70 Spom
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC14C4.01c
  label: atg43 Spom
  type: gocam:Object
- id: PomBase:SPAC6F12.07
  label: tom20 Spom
  type: gocam:Object
- id: ECO:0005647
  label: isothermal titration calorimetry evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC19G7.19
  label: tom5 Spom
  type: gocam:Object
- id: PomBase:SPAC823.17
  label: tom6 Spom
  type: gocam:Object
- id: PomBase:SPBC27B12.10c
  label: tom7 Spom
  type: gocam:Object
- id: PomBase:SPAC1B2.02c
  label: ugo1 Spom
  type: gocam:Object
- id: PomBase:SPBC1706.03
  label: fzo1 Spom
  type: gocam:Object
- id: PomBase:SPBC11C11.06c
  label: mom14 Spom
  type: gocam:Object
- id: PomBase:SPAC29A4.17c
  label: fun14 Spom
  type: gocam:Object
- id: PomBase:SPBC1718.06
  label: msp1 Spom
  type: gocam:Object
- id: PomBase:SPAC19A8.14
  label: pth2 Spom
  type: gocam:Object
- id: PomBase:SPAC1A6.10
  label: tcd1 Spom
  type: gocam:Object
- id: PomBase:SPCC320.04c
  label: gem1 Spom
  type: gocam:Object
- id: PomBase:SPBC11G11.01
  label: fis1 Spom
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-04-15'
  provided_by:
  - http://www.pombase.org
