id: gomodel:66c7d41500000963
title: thiamine-containing compound metabolic process (GO:0042723)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-04-02'
activities:
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    term: GO:0005829
- id: gomodel:66c7d41500000963/69a0c46f00002264
  term: CHEBI:43474
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2026-03-09'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:66c7d41500000963/69a0c46f00002232
  term: CHEBI:157692
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2026-03-09'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:66c7d41500000963/69a0c46f00002247
  term: CHEBI:90873
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2026-03-09'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:66c7d41500000963/69a0c46f00002250
  term: CHEBI:139151
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2026-03-09'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:66c7d41500000963/66c7d41500001063
  term: CHEBI:58937
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2026-01-12'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:66c7d41500000963/69c59f8a00001733
  term: PomBase:SPCC1223.02
objects:
- id: GO:0106344
  label: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from
    histidine and PLP
  type: gocam:Object
- id: PomBase:SPCC1223.02
  label: nmt1 Spom
  type: gocam:Object
- id: GO:0009228
  label: thiamine biosynthetic process
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:29979
  label: L-histidine residue
  type: gocam:Object
- id: CHEBI:143915
  label: N(6)-(pyridoxal phosphate)-L-lysine(2-) residue
  type: gocam:Object
- id: CHEBI:16892
  label: 4-amino-5-hydroxymethyl-2-methylpyrimidine
  type: gocam:Object
- id: CHEBI:58354
  label: 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-)
  type: gocam:Object
- id: GO:0008902
  label: hydroxymethylpyrimidine kinase activity
  type: gocam:Object
- id: PomBase:SPBP8B7.17c
  label: thi20 Spom
  type: gocam:Object
- id: PomBase:SPBP8B7.18c
  label: thi201 Spom
  type: gocam:Object
- id: PomBase:SPCC18B5.05c
  label: SPCC18B5.05c Spom
  type: gocam:Object
- id: GO:0008972
  label: phosphomethylpyrimidine kinase activity
  type: gocam:Object
- id: CHEBI:57841
  label: 4-amino-2-methyl-5-diphosphonatooxymethylpyrimidine(3-)
  type: gocam:Object
- id: GO:0160205
  label: cysteine-dependent adenosine diphosphate thiazole synthase activity
  type: gocam:Object
- id: PomBase:SPBC26H8.01
  label: thi2 Spom
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: CHEBI:17957
  label: 5-(2-hydroxyethyl)-4-methylthiazole
  type: gocam:Object
- id: GO:0004417
  label: hydroxyethylthiazole kinase activity
  type: gocam:Object
- id: PomBase:SPAC23H4.10c
  label: thi4 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58296
  label: 4-methyl-5-(2-phosphonatooxyethyl)thiazole(2-)
  type: gocam:Object
- id: GO:0004789
  label: thiamine-phosphate diphosphorylase activity
  type: gocam:Object
- id: CHEBI:18385
  label: thiamine(1+)
  type: gocam:Object
- id: GO:0004788
  label: thiamine diphosphokinase activity
  type: gocam:Object
- id: PomBase:SPAC6F12.05c
  label: tnr3 Spom
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58937
  label: thiamine(1+) diphosphate(3-)
  type: gocam:Object
- id: GO:0001228
  label: DNA-binding transcription activator activity, RNA polymerase II-specific
  type: gocam:Object
- id: PomBase:SPAC1486.10
  label: thi1 Spom
  type: gocam:Object
- id: GO:0090180
  label: positive regulation of thiamine biosynthetic process
  type: gocam:Object
- id: PomBase:SPBP8B7.30c
  label: thi5 Spom
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:29034
  label: iron(3+)
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: CHEBI:157692
  label: (2S)-2-amino-5-hydroxy-4-oxopentanoate residue
  type: gocam:Object
- id: CHEBI:29969
  label: L-lysinium residue
  type: gocam:Object
- id: CHEBI:29033
  label: iron(2+)
  type: gocam:Object
- id: CHEBI:29950
  label: L-cysteine residue
  type: gocam:Object
- id: CHEBI:57305
  label: glycine zwitterion
  type: gocam:Object
- id: CHEBI:90873
  label: dehydroalanine residue
  type: gocam:Object
- id: CHEBI:139151
  label: ADP-5-ethyl-4-methylthiazole-2-carboxylate(3-)
  type: gocam:Object
- id: CHEBI:17154
  label: nicotinamide
  type: gocam:Object
- id: CHEBI:37575
  label: thiamine(1+) monophosphate(2-)
  type: gocam:Object
- id: CHEBI:43474
  label: hydrogenphosphate
  type: gocam:Object
- id: CHEBI:33019
  label: diphosphate(3-)
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: CHEBI:33190
  label: 3-oxopropanoate
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: GO:0042131
  label: thiamine phosphate phosphatase activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0009229
  label: thiamine diphosphate biosynthetic process
  type: gocam:Object
- id: GO:0005634
  label: nucleus
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0090422
  label: thiamine pyrophosphate transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPBC1604.04
  label: SPBC1604.04 Spom
  type: gocam:Object
- id: GO:1990545
  label: mitochondrial thiamine pyrophosphate transmembrane transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-04-02'
  provided_by:
  - http://www.pombase.org
