id: gomodel:66187e4700003150
title: adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-20'
activities:
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    term: PomBase:SPAC926.04c
  molecular_function:
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  occurs_in:
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    - term: ECO:0000318
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      with_objects:
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      - UniProtKB:P11501
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  part_of:
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      term: GO:0010619
  causal_associations:
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      term: GO:1990243
  molecular_function:
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      term: GO:0005952
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    - term: ECO:0000318
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    term: PomBase:SPAC6F12.02
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      - RGD:2595
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    - term: ECO:0000318
      reference: GO_REF:0000033
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      reference: GO_REF:0000024
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    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
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      - SGD:S000004369
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molecules:
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  term: CHEBI:17634
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    term: GO:0005576
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  term: CHEBI:456215
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    type: CellularAnatomicalEntityAssociation
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    term: GO:0005829
- id: gomodel:66187e4700003150/69b3372b00002614
  term: PomBase:SPBC1198.14c
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  term: PomBase:SPCC285.09c
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  term: PomBase:SPCC285.09c
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  term: CHEBI:30616
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    term: GO:0005829
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  term: CHEBI:58165
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    term: GO:0005829
objects:
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  type: gocam:Object
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  label: git3 Spom
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- id: GO:0010619
  label: adenylate cyclase-activating glucose-activated G protein-coupled receptor
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  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: GO:0010856
  label: adenylate cyclase activator activity
  type: gocam:Object
- id: PomBase:SPAC23H3.13c
  label: gpa2 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004016
  label: adenylate cyclase activity
  type: gocam:Object
- id: PomBase:SPBC19C7.03
  label: cyr1 Spom
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: GO:0005886
  label: plasma membrane
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:456215
  label: adenosine 5'-monophosphate(2-)
  type: gocam:Object
- id: CHEBI:58165
  label: 3',5'-cyclic AMP(1-)
  type: gocam:Object
- id: GO:0004115
  label: 3',5'-cyclic-AMP phosphodiesterase activity
  type: gocam:Object
- id: PomBase:SPCC285.09c
  label: cgs2 Spom
  type: gocam:Object
- id: GO:0110034
  label: negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled
    receptor signaling pathway
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004674
  label: protein serine/threonine kinase activity
  type: gocam:Object
- id: PomBase:SPBC106.10
  label: pka1 Spom
  type: gocam:Object
- id: CHEBI:17634
  label: D-glucose
  type: gocam:Object
- id: GO:0004862
  label: cAMP-dependent protein kinase inhibitor activity
  type: gocam:Object
- id: PomBase:SPAC8C9.03
  label: cgs1 Spom
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC1B9.02c
  label: sck1 Spom
  type: gocam:Object
- id: GO:0008179
  label: adenylate cyclase binding
  type: gocam:Object
- id: PomBase:SPCC306.09c
  label: cap1 Spom
  type: gocam:Object
- id: ECO:0000353
  label: physical interaction evidence used in manual assertion
  type: gocam:Object
- id: GO:0003674
  label: molecular_function
  type: gocam:Object
- id: PomBase:SPBC21C3.20c
  label: git1 Spom
  type: gocam:Object
- id: GO:0051087
  label: protein-folding chaperone binding
  type: gocam:Object
- id: PomBase:SPBC36.12c
  label: git7 Spom
  type: gocam:Object
- id: CHEBI:30616
  label: ATP(4-)
  type: gocam:Object
- id: GO:0005576
  label: extracellular region
  type: gocam:Object
- id: GO:0044183
  label: protein folding chaperone
  type: gocam:Object
- id: PomBase:SPAC926.04c
  label: hsp90 Spom
  type: gocam:Object
- id: GO:0006457
  label: protein folding
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0001228
  label: DNA-binding transcription activator activity, RNA polymerase II-specific
  type: gocam:Object
- id: PomBase:SPAC6F12.02
  label: rst2 Spom
  type: gocam:Object
- id: GO:0045944
  label: positive regulation of transcription by RNA polymerase II
  type: gocam:Object
- id: GO:0005634
  label: nucleus
  type: gocam:Object
- id: GO:0042132
  label: fructose 1,6-bisphosphate 1-phosphatase activity
  type: gocam:Object
- id: PomBase:SPBC1198.14c
  label: fbp1 Spom
  type: gocam:Object
- id: GO:0006094
  label: gluconeogenesis
  type: gocam:Object
- id: PomBase:SPBC215.04
  label: git11 Spom
  type: gocam:Object
- id: GO:0031234
  label: extrinsic component of cytoplasmic side of plasma membrane
  type: gocam:Object
- id: GO:0005834
  label: heterotrimeric G-protein complex
  type: gocam:Object
- id: GO:0030159
  label: signaling receptor complex adaptor activity
  type: gocam:Object
- id: PomBase:SPBC32H8.07
  label: git5 Spom
  type: gocam:Object
- id: GO:0005085
  label: guanyl-nucleotide exchange factor activity
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC29B5.01
  label: atf1 Spom
  type: gocam:Object
- id: GO:1990243
  label: atf1-pcr1 complex
  type: gocam:Object
- id: PomBase:SPAC21E11.03c
  label: pcr1 Spom
  type: gocam:Object
- id: GO:0006995
  label: cellular response to nitrogen starvation
  type: gocam:Object
- id: GO:0007189
  label: adenylate cyclase-activating G protein-coupled receptor signaling pathway
  type: gocam:Object
- id: GO:0042149
  label: cellular response to glucose starvation
  type: gocam:Object
- id: GO:0005952
  label: cAMP-dependent protein kinase complex
  type: gocam:Object
- id: GO:0045722
  label: positive regulation of gluconeogenesis
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-03-20'
  provided_by:
  - http://www.pombase.org
