id: gomodel:66a3e0bb00002988
title: pteridine-containing compound metabolic process (GO:0042558) - mitochondrial
taxon: NCBITaxon:4896
status: production
date_modified: '2026-02-20'
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      provided_by:
      - http://www.pombase.org
    term: GO:0005829
objects:
- id: CHEBI:57453
  label: (6S)-5,6,7,8-tetrahydrofolate(2-)
  type: gocam:Object
- id: GO:0004372
  label: glycine hydroxymethyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC18G6.04c
  label: shm2 Spom
  type: gocam:Object
- id: GO:0046653
  label: tetrahydrofolate metabolic process
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004146
  label: dihydrofolate reductase activity
  type: gocam:Object
- id: PomBase:SPCC1223.08c
  label: dfr1 Spom
  type: gocam:Object
- id: GO:0046655
  label: folic acid metabolic process
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:57457
  label: (6S)-5-formyltetrahydrofolate(2-)
  type: gocam:Object
- id: GO:0030272
  label: 5-formyltetrahydrofolate cyclo-ligase activity
  type: gocam:Object
- id: PomBase:SPBC1703.08c
  label: fau1 Spom
  type: gocam:Object
- id: GO:0009396
  label: folic acid-containing compound biosynthetic process
  type: gocam:Object
- id: GO:0004488
  label: methylenetetrahydrofolate dehydrogenase (NADP+) activity
  type: gocam:Object
- id: PomBase:SPBC2G2.08
  label: ade9 Spom
  type: gocam:Object
- id: GO:0009257
  label: 10-formyltetrahydrofolate biosynthetic process
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0004477
  label: methenyltetrahydrofolate cyclohydrolase activity
  type: gocam:Object
- id: GO:0004489
  label: methylenetetrahydrofolate reductase [NAD(P)H] activity
  type: gocam:Object
- id: PomBase:SPAC56F8.10
  label: met9 Spom
  type: gocam:Object
- id: GO:0035999
  label: tetrahydrofolate interconversion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: GO:0004326
  label: tetrahydrofolylpolyglutamate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1709.17
  label: met7 Spom
  type: gocam:Object
- id: GO:0046901
  label: tetrahydrofolylpolyglutamate biosynthetic process
  type: gocam:Object
- id: PomBase:SPAC227.09
  label: fol3 Spom
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0004329
  label: formate-tetrahydrofolate ligase activity
  type: gocam:Object
- id: GO:0008841
  label: dihydrofolate synthase activity
  type: gocam:Object
- id: GO:0004156
  label: dihydropteroate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1734.03
  label: fol1 Spom
  type: gocam:Object
- id: GO:0046656
  label: folic acid biosynthetic process
  type: gocam:Object
- id: GO:0008696
  label: 4-amino-4-deoxychorismate lyase activity
  type: gocam:Object
- id: PomBase:SPBC19G7.02
  label: abz2 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0046820
  label: aminodeoxychorismate synthase activity
  type: gocam:Object
- id: PomBase:SPBP8B7.29
  label: abz1 Spom
  type: gocam:Object
- id: CHEBI:29748
  label: chorismate(2-)
  type: gocam:Object
- id: CHEBI:58406
  label: 4-amino-4-deoxychorismate(1-)
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: CHEBI:17836
  label: 4-aminobenzoate
  type: gocam:Object
- id: CHEBI:17839
  label: 7,8-dihydropteroate
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: CHEBI:57451
  label: dihydrofolate(2-)
  type: gocam:Object
- id: GO:0003848
  label: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
  type: gocam:Object
- id: GO:0004150
  label: dihydroneopterin aldolase activity
  type: gocam:Object
- id: CHEBI:44841
  label: 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one
  type: gocam:Object
- id: CHEBI:17071
  label: glycolaldehyde
  type: gocam:Object
- id: CHEBI:17001
  label: 7,8-dihydroneopterin
  type: gocam:Object
- id: CHEBI:195366
  label: (6R)-10-formyltetrahydrofolate(2-)
  type: gocam:Object
- id: GO:0005740
  label: mitochondrial envelope
  type: gocam:Object
- id: GO:0008517
  label: folic acid transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPBC27B12.09c
  label: flx1 Spom
  type: gocam:Object
- id: GO:0055085
  label: transmembrane transport
  type: gocam:Object
- id: GO:0042558
  label: pteridine-containing compound metabolic process
  type: gocam:Object
- id: CHEBI:58359
  label: L-glutamine zwitterion
  type: gocam:Object
- id: CHEBI:29985
  label: L-glutamate(1-)
  type: gocam:Object
- id: CHEBI:15361
  label: pyruvate
  type: gocam:Object
- id: CHEBI:72950
  label: (7,8-dihydropterin-6-yl)methyl diphosphate(3-)
  type: gocam:Object
- id: CHEBI:33384
  label: L-serine zwitterion
  type: gocam:Object
- id: CHEBI:57305
  label: glycine zwitterion
  type: gocam:Object
- id: CHEBI:15636
  label: (6R)-5,10-methylenetetrahydrofolate(2-)
  type: gocam:Object
- id: CHEBI:15740
  label: formate
  type: gocam:Object
- id: CHEBI:18608
  label: (6S)-5-methyltetrahydrofolate(2-)
  type: gocam:Object
- id: CHEBI:57455
  label: (6R)-5,10-methenyltetrahydrofolate
  type: gocam:Object
- id: GO:0004479
  label: methionyl-tRNA formyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC1805.09c
  label: fmt1 Spom
  type: gocam:Object
- id: GO:0070124
  label: mitochondrial translational initiation
  type: gocam:Object
- id: CHEBI:141005
  label: (6S)-5,6,7,8-tetrahydrofolyl-poly(gamma-glutamate) macromolecule
  type: gocam:Object
- id: GO:0003864
  label: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC5H10.09c
  label: ecm31 Spom
  type: gocam:Object
- id: GO:0015940
  label: pantothenate biosynthetic process
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: CHEBI:11851
  label: 3-methyl-2-oxobutanoate
  type: gocam:Object
- id: CHEBI:11561
  label: 2-dehydropantoate
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-02-20'
  provided_by:
  - http://www.pombase.org
