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Reference - GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference

Reference summary

PubMed ID
GO_REF:0000111
Title
Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
Authors
TBD
Abstract
The Gene Ontology Consortium uses the IC (Inferred by Curator; ECO:0000305) evidence code when assignment of a GO term cannot be supported by direct experimental or sequence-based evidence, but can, based on a curator’s biological knowledge, be reasonably inferred from existing GO annotations to the same gene/gene product. Use of the IC evidence code with GO_REF:0000111 indicates that a curator inferred the GO term based on at least one supporting annotation with an 'Inferred from Sequence Similarity' (ISS; ECO:0000250) evidence code. Note that additional supporting annotations may be experimentally evidenced. When using GO_REF:0000111, the 'with/from' field must contain all GO identifiers used as supporting annotations.

Annotation

GO biological process

GO:0071266 - 'de novo' L-methionine biosynthetic process

Genes:

GO:0044571 - [2Fe-2S] cluster assembly

Genes:

GO:0019427 - acetyl-CoA biosynthetic process from acetate

Genes:

GO:0006637 - acyl-CoA metabolic process

Genes:

GO:0098702 - adenine import across plasma membrane

Genes:

GO:0006169 - adenosine salvage

Genes:

GO:0006520 - amino acid metabolic process

Genes:

GO:0006422 - aspartyl-tRNA aminoacylation

Genes:

GO:0051315 - attachment of mitotic spindle microtubules to kinetochore

Genes:

GO:0061762 - CAMKK-AMPK signaling cascade

Genes:

GO:0061621 - canonical glycolysis

Genes:

GO:0016052 - carbohydrate catabolic process

Genes:

GO:0034219 - carbohydrate transmembrane transport

Genes:

GO:0007166 - cell surface receptor signaling pathway

Genes:

GO:0044347 - cell wall polysaccharide catabolic process

Genes:

GO:1990748 - cellular detoxification

Genes:

GO:0061692 - cellular detoxification of hydrogen peroxide

Genes:

GO:0070458 - cellular detoxification of nitrogen compound

Genes:

GO:0098869 - cellular oxidant detoxification

Genes:

GO:0034080 - CENP-A containing chromatin assembly

Genes:

GO:0009423 - chorismate biosynthetic process

Genes:

GO:0006338 - chromatin remodeling

Genes:

GO:0006101 - citrate metabolic process

Genes:

GO:0072583 - clathrin-dependent endocytosis

Genes:

GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Genes:

GO:0140529 - CMG complex assembly

Genes:

GO:0180010 - co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

Genes:

GO:1903607 - cytochrome c biosynthetic process

Genes:

GO:0031122 - cytoplasmic microtubule organization

Genes:

GO:0002181 - cytoplasmic translation

Genes:

GO:0002182 - cytoplasmic translational elongation

Genes:

GO:0002184 - cytoplasmic translational termination

Genes:

GO:0015964 - diadenosine triphosphate catabolic process

Genes:

GO:0050992 - dimethylallyl diphosphate biosynthetic process

Genes:

GO:0071897 - DNA biosynthetic process

Genes:

GO:0006308 - DNA catabolic process

Genes:

GO:0140861 - DNA repair-dependent chromatin remodeling

Genes:

GO:0006270 - DNA replication initiation

Genes:

GO:0006335 - DNA replication-dependent chromatin assembly

Genes:

GO:0180047 - dolichol phosphate mannose biosynthetic process

Genes:

GO:0006488 - dolichol-linked oligosaccharide biosynthetic process

Genes:

GO:0000724 - double-strand break repair via homologous recombination

Genes:

GO:0030989 - dynein-driven meiotic oscillatory nuclear movement

Genes:

GO:0006112 - energy reserve metabolic process

Genes:

GO:0006887 - exocytosis

Genes:

GO:0010142 - farnesyl diphosphate biosynthetic process, mevalonate pathway

Genes:

GO:0006633 - fatty acid biosynthetic process

Genes:

GO:0046656 - folic acid biosynthetic process

Genes:

GO:0070879 - fungal-type cell wall beta-glucan metabolic process

Genes:

GO:0033499 - galactose catabolic process via UDP-galactose, Leloir pathway

Genes:

GO:0009298 - GDP-mannose biosynthetic process

Genes:

GO:0006091 - generation of precursor metabolites and energy

Genes:

GO:0061610 - glycerol catabolic process to glycerone phosphate

Genes:

GO:0046168 - glycerol-3-phosphate catabolic process

Genes:

GO:0046037 - GMP metabolic process

Genes:

GO:0032263 - GMP salvage

Genes:

GO:0006183 - GTP biosynthetic process

Genes:

GO:0098710 - guanine import across plasma membrane

Genes:

GO:0120010 - intermembrane phospholipid transfer

Genes:

GO:0120011 - intermembrane sterol transfer

Genes:

GO:0006891 - intra-Golgi vesicle-mediated transport

Genes:

GO:0035556 - intracellular signal transduction

Genes:

GO:0042852 - L-alanine biosynthetic process

Genes:

GO:0042853 - L-alanine catabolic process

Genes:

GO:0019344 - L-cysteine biosynthetic process

Genes:

GO:0097054 - L-glutamate biosynthetic process

Genes:

GO:0006555 - L-methionine metabolic process

Genes:

GO:0045324 - late endosome to vacuole transport

Genes:

GO:0016042 - lipid catabolic process

Genes:

GO:0019915 - lipid storage

Genes:

GO:0009107 - lipoate biosynthetic process

Genes:

GO:0016236 - macroautophagy

Genes:

GO:0043490 - malate-aspartate shuttle

Genes:

GO:2001295 - malonyl-CoA biosynthetic process

Genes:

GO:0051999 - mannosyl-inositol phosphorylceramide biosynthetic process

Genes:

GO:0061024 - membrane organization

Genes:

GO:0051596 - methylglyoxal catabolic process

Genes:

GO:1990544 - mitochondrial ATP transmembrane transport

Genes:

GO:0032042 - mitochondrial DNA metabolic process

Genes:

GO:0043504 - mitochondrial DNA repair

Genes:

GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen

Genes:

GO:0006120 - mitochondrial electron transport, NADH to ubiquinone

Genes:

GO:0140053 - mitochondrial gene expression

Genes:

GO:0007006 - mitochondrial membrane organization

Genes:

GO:0034982 - mitochondrial protein processing

Genes:

GO:0032543 - mitochondrial translation

Genes:

GO:0070125 - mitochondrial translational elongation

Genes:

GO:1990799 - mitochondrial tRNA wobble position uridine thiolation

Genes:

GO:0007005 - mitochondrion organization

Genes:

GO:1990456 - mitochondrion-endoplasmic reticulum membrane tethering

Genes:

GO:0000423 - mitophagy

Genes:

GO:1902975 - mitotic DNA replication initiation

Genes:

GO:0000070 - mitotic sister chromatid segregation

Genes:

GO:0051306 - mitotic sister chromatid separation

Genes:

GO:0000395 - mRNA 5'-splice site recognition

Genes:

GO:0045292 - mRNA cis splicing, via spliceosome

Genes:

GO:0034355 - NAD+ biosynthetic process via the salvage pathway

Genes:

GO:0006740 - NADPH regeneration

Genes:

GO:0110034 - negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway

Genes:

GO:0045814 - negative regulation of gene expression, epigenetic

Genes:

GO:0045721 - negative regulation of gluconeogenesis

Genes:

GO:0045820 - negative regulation of glycolytic process

Genes:

GO:0000122 - negative regulation of transcription by RNA polymerase II

Genes:

GO:0098863 - nuclear migration by microtubule mediated pushing forces

Genes:

GO:0071039 - nuclear polyadenylation-dependent CUT catabolic process

Genes:

GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Genes:

GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening

Genes:

GO:0034655 - nucleobase-containing compound catabolic process

Genes:

GO:0009225 - nucleotide-sugar metabolic process

Genes:

GO:0009313 - oligosaccharide catabolic process

Genes:

GO:0006730 - one-carbon metabolic process

Genes:

GO:0009051 - pentose-phosphate shunt, oxidative branch

Genes:

GO:0006656 - phosphatidylcholine biosynthetic process

Genes:

GO:0006646 - phosphatidylethanolamine biosynthetic process

Genes:

GO:0046488 - phosphatidylinositol metabolic process

Genes:

GO:0007009 - plasma membrane organization

Genes:

GO:0016973 - poly(A)+ mRNA export from nucleus

Genes:

GO:0180042 - polyphosphate import into vacuole

Genes:

GO:0000272 - polysaccharide catabolic process

Genes:

GO:0070452 - positive regulation of ergosterol biosynthetic process

Genes:

GO:0045722 - positive regulation of gluconeogenesis

Genes:

GO:0045821 - positive regulation of glycolytic process

Genes:

GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Genes:

GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Genes:

GO:0006457 - protein folding

Genes:

GO:0034975 - protein folding in endoplasmic reticulum

Genes:

GO:0030150 - protein import into mitochondrial matrix

Genes:

GO:0045048 - protein insertion into ER membrane

Genes:

GO:0009249 - protein lipoylation

Genes:

GO:0072659 - protein localization to plasma membrane

Genes:

GO:0051604 - protein maturation

Genes:

GO:0030091 - protein repair

Genes:

GO:0065003 - protein-containing complex assembly

Genes:

GO:1902600 - proton transmembrane transport

Genes:

GO:0006782 - protoporphyrinogen IX biosynthetic process

Genes:

GO:0009216 - purine deoxyribonucleoside triphosphate biosynthetic process

Genes:

GO:0042278 - purine nucleoside metabolic process

Genes:

GO:0042818 - pyridoxamine metabolic process

Genes:

GO:0009212 - pyrimidine deoxyribonucleoside triphosphate biosynthetic process

Genes:

GO:0006206 - pyrimidine nucleobase metabolic process

Genes:

GO:0006213 - pyrimidine nucleoside metabolic process

Genes:

GO:0006086 - pyruvate decarboxylation to acetyl-CoA

Genes:

GO:0019660 - pyruvate fermentation

Genes:

GO:2000765 - regulation of cytoplasmic translation

Genes:

GO:0033157 - regulation of intracellular protein transport

Genes:

GO:1903432 - regulation of TORC1 signaling

Genes:

GO:1903469 - removal of RNA primer involved in mitotic DNA replication

Genes:

GO:0000301 - retrograde transport, vesicle recycling within Golgi

Genes:

GO:0009191 - ribonucleoside diphosphate catabolic process

Genes:

GO:0031167 - rRNA methylation

Genes:

GO:0006364 - rRNA processing

Genes:

GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Genes:

GO:0007165 - signal transduction

Genes:

GO:0023052 - signaling

Genes:

GO:0030466 - silent mating-type cassette heterochromatin formation

Genes:

GO:0000452 - snoRNA guided rRNA 2'-O-methylation

Genes:

GO:0036376 - sodium ion export across plasma membrane

Genes:

GO:1903710 - spermine transmembrane transport

Genes:

GO:0046512 - sphingosine biosynthetic process

Genes:

GO:0051455 - spindle attachment to meiosis I kinetochore

Genes:

GO:0006614 - SRP-dependent cotranslational protein targeting to membrane

Genes:

GO:0016125 - sterol metabolic process

Genes:

GO:0031509 - subtelomeric heterochromatin formation

Genes:

GO:0071816 - tail-anchored membrane protein insertion into ER membrane

Genes:

GO:0046901 - tetrahydrofolylpolyglutamate biosynthetic process

Genes:

GO:0033013 - tetrapyrrole metabolic process

Genes:

GO:0006368 - transcription elongation by RNA polymerase II

Genes:

GO:0140673 - transcription elongation-coupled chromatin remodeling

Genes:

GO:0006367 - transcription initiation at RNA polymerase II promoter

Genes:

GO:0045815 - transcription initiation-coupled chromatin remodeling

Genes:

GO:0006283 - transcription-coupled nucleotide-excision repair

Genes:

GO:0055085 - transmembrane transport

Genes:

GO:0019433 - triglyceride catabolic process

Genes:

GO:0002946 - tRNA C5-cytosine methylation

Genes:

GO:0030488 - tRNA methylation

Genes:

GO:0002940 - tRNA N2-guanine methylation

Genes:

GO:0002949 - tRNA threonylcarbamoyladenosine modification

Genes:

GO:0002100 - tRNA wobble adenosine to inosine editing

Genes:

GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Genes:

GO:0006223 - uracil salvage

Genes:

GO:0000050 - urea cycle

Genes:

GO:0019627 - urea metabolic process

Genes:

GO:0007035 - vacuolar acidification

Genes:

GO:0007034 - vacuolar transport

Genes:

GO:0048278 - vesicle docking

Genes:

GO:0090522 - vesicle tethering involved in exocytosis

Genes:

GO:0032265 - XMP salvage

Genes:

GO cellular component

GO:0000148 - 1,3-beta-D-glucan synthase complex

Genes:

GO:0005938 - cell cortex

Genes:

GO:0009986 - cell surface

Genes:

GO:0000785 - chromatin

Genes:

GO:0005801 - cis-Golgi network

Genes:

GO:0005737 - cytoplasm

Genes:

GO:0098554 - cytoplasmic side of endoplasmic reticulum membrane

Genes:

GO:0032473 - cytoplasmic side of mitochondrial outer membrane

Genes:

GO:0005829 - cytosol

Genes:

GO:0022626 - cytosolic ribosome

Genes:

GO:0031261 - DNA replication preinitiation complex

Genes:

GO:0005788 - endoplasmic reticulum lumen

Genes:

GO:0005789 - endoplasmic reticulum membrane

Genes:

GO:0098853 - endoplasmic reticulum-vacuole membrane contact site

Genes:

GO:0009897 - external side of plasma membrane

Genes:

GO:0005576 - extracellular region

Genes:

GO:0031314 - extrinsic component of mitochondrial inner membrane

Genes:

GO:0009277 - fungal-type cell wall

Genes:

GO:0000329 - fungal-type vacuole membrane

Genes:

GO:0000139 - Golgi membrane

Genes:

GO:0000776 - kinetochore

Genes:

GO:1990819 - mating projection actin fusion focus

Genes:

GO:0043332 - mating projection tip

Genes:

GO:0099617 - matrix side of mitochondrial inner membrane

Genes:

GO:0016020 - membrane

Genes:

GO:0005875 - microtubule associated complex

Genes:

GO:0000262 - mitochondrial chromosome

Genes:

GO:0005743 - mitochondrial inner membrane

Genes:

GO:0005759 - mitochondrial matrix

Genes:

GO:0005739 - mitochondrion

Genes:

GO:0043596 - nuclear replication fork

Genes:

GO:0005730 - nucleolus

Genes:

GO:0005634 - nucleus

Genes:

GO:0000407 - phagophore assembly site

Genes:

GO:0031201 - SNARE complex

Genes:

GO:0005681 - spliceosomal complex

Genes:

GO:0009361 - succinate-CoA ligase complex (ADP-forming)

Genes:

GO:0043528 - tRNA (m2G10) methyltransferase complex

Genes:

GO:0106143 - tRNA (m7G46) methyltransferase complex

Genes:

GO:0071006 - U2-type catalytic step 1 spliceosome

Genes:

GO:0043541 - UDP-N-acetylglucosamine transferase complex

Genes:

GO molecular function

GO:0000515 - aspartate:glutamate, proton antiporter activity

Genes:

GO:0016887 - ATP hydrolysis activity

Genes:

GO:0034513 - box H/ACA snoRNA binding

Genes:

GO:0035615 - clathrin-cargo adaptor activity

Genes:

GO:0003677 - DNA binding

Genes:

GO:0030942 - endoplasmic reticulum signal peptide binding

Genes:

GO:0005525 - GTP binding

Genes:

GO:0000511 - H2A-H2B histone complex chaperone activity

Genes:

GO:0000510 - H3-H4 histone complex chaperone activity

Genes:

GO:0032977 - membrane insertase activity

Genes:

GO:0140474 - mitochondrion-endoplasmic reticulum membrane tether activity

Genes:

GO:0120014 - phospholipid transfer activity

Genes:

GO:0043495 - protein-membrane adaptor activity

Genes:

GO:0000340 - RNA 7-methylguanosine cap binding

Genes:

GO:0001181 - RNA polymerase I general transcription initiation factor activity

Genes:

GO:0016251 - RNA polymerase II general transcription initiation factor activity

Genes:

GO:0000995 - RNA polymerase III general transcription initiation factor activity

Genes:

GO:0019843 - rRNA binding

Genes:

GO:0030527 - structural constituent of chromatin

Genes:

GO:0003713 - transcription coactivator activity

Genes:

GO:0003714 - transcription corepressor activity

Genes:

GO:0003711 - transcription elongation factor activity

Genes:

GO:0003747 - translation release factor activity

Genes:

GO:0000049 - tRNA binding

Genes:

GO:0033410 - UAC codon-amino acid adaptor activity

Genes: