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Reference - GO_REF:0000116 - Automatic Gene Ontology annotation based on Rhea mapping.

Reference summary

PubMed ID
GO_REF:0000116
Title
Automatic Gene Ontology annotation based on Rhea mapping.
Authors
GO Central curators, GOA curators, Rhea curators
Abstract
Rhea (https://www.rhea-db.org/, PMID:30272209) is an expert-curated knowledgebase of chemical and transport reactions of biological interest - and the standard for enzyme and transporter annotation in UniProtKB (PMID:31688925). Rhea uses the chemical dictionary ChEBI (Chemical Entities of Biological Interest) to describe reaction participants and their chemical transformations in a computationally tractable manner. GO terms corresponding to Rhea reactions are assigned a Rhea database cross-reference. The corresponding GO term is automatically applied to all UniProt entries annotated with a Rhea reaction. The mapping file is available at: http://current.geneontology.org/ontology/external2go/rhea2go.

Annotation

GO molecular function

GO:0120568 - (R)-2-hydroxyglutarate (NAD+) dehydrogenase activity

Genes:

GO:0106262 - 1-acylglycerophosphoethanolamine O-acyltransferase activity

Genes:

GO:0120538 - 2-methoxy-6-polyprenolphenol 4-hydroxylase activity

Genes:

GO:0061542 - 3-demethylubiquinol 3-O-methyltransferase activity

Genes:

GO:0120537 - 3-demethylubiquinone 3-O-methyltransferase activity

Genes:

GO:0106364 - 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity

Genes:

GO:0010308 - acireductone dioxygenase (Ni2+-requiring) activity

Genes:

GO:0003825 - alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

Genes:

GO:0047657 - alpha-1,3-glucan synthase activity

Genes:

GO:0160205 - cysteine-dependent adenosine diphosphate thiazole synthase activity

Genes:

GO:0043771 - cytidine kinase activity

Genes:

GO:0106430 - dihydroorotate dehydrogenase (quinone) activity

Genes:

GO:0061685 - diphthine methylesterase activity

Genes:

GO:0034061 - DNA polymerase activity

Genes:

GO:0052926 - dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity

Genes:

GO:0052918 - dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity

Genes:

GO:0016297 - fatty acyl-[ACP] hydrolase activity

Genes:

GO:0004328 - formamidase activity

Genes:

GO:0004359 - glutaminase activity

Genes:

GO:0045174 - glutathione dehydrogenase (ascorbate) activity

Genes:

GO:0004364 - glutathione transferase activity

Genes:

GO:0141152 - glycerol-3-phosphate dehydrogenase (NAD+) activity

Genes:

GO:0033971 - hydroxyisourate hydrolase activity

Genes:

GO:0000823 - inositol-1,4,5-trisphosphate 6-kinase activity

Genes:

GO:0061710 - L-threonylcarbamoyladenylate synthase activity

Genes:

GO:0016979 - lipoate-protein ligase activity

Genes:

GO:0004475 - mannose-1-phosphate guanylyltransferase (GTP) activity

Genes:

GO:0106312 - methylenetetrahydrofolate reductase (NADH) activity

Genes:

GO:0106313 - methylenetetrahydrofolate reductase (NADPH) activity

Genes:

GO:0046421 - methylisocitrate lyase activity

Genes:

GO:0120555 - NADH dehydrogenase (ubiquinone) (non-electrogenic) activity

Genes:

GO:0003959 - NADPH dehydrogenase activity

Genes:

GO:0008948 - oxaloacetate decarboxylase activity

Genes:

GO:0003755 - peptidyl-prolyl cis-trans isomerase activity

Genes:

GO:0004622 - phosphatidylcholine lysophospholipase A1 activity

Genes:

GO:0004665 - prephenate dehydrogenase (NADP+) activity

Genes:

GO:0120518 - protein N-terminal-methionine acetyltransferase activity

Genes:

GO:0016279 - protein-lysine N-methyltransferase activity

Genes:

GO:0008999 - protein-N-terminal-alanine acetyltransferase activity

Genes:

GO:0120159 - rRNA pseudouridine synthase activity

Genes:

GO:0051266 - sirohydrochlorin ferrochelatase activity

Genes:

GO:0008177 - succinate dehydrogenase (quinone) activity

Genes:

GO:0019166 - trans-2-enoyl-CoA reductase (NADPH) activity

Genes:

GO:0004806 - triacylglycerol lipase activity

Genes:

GO:0050354 - triokinase activity

Genes:

GO:0061711 - tRNA N(6)-L-threonylcarbamoyladenine synthase activity

Genes:

GO:0141101 - tRNA(Ser) (uridine(44)-2'-O-ribose)-methyltransferase activity

Genes:

GO:0102521 - tRNA-4-demethylwyosine synthase activity

Genes:

GO:0004835 - tubulin-tyrosine ligase activity

Genes:

GO:0004849 - uridine kinase activity

Genes:

GO:0141040 - very-long-chain 3-oxoacyl-CoA reductase activity

Genes: