Reference - PMID:10525840 - Cloning of Schizosaccharomyces pombe bio2 by heterologous complementation of a Saccharomyces cerevisiae mutant.
Reference summary
- PubMed ID
- PMID:10525840
- Title
- Cloning of Schizosaccharomyces pombe bio2 by heterologous complementation of a Saccharomyces cerevisiae mutant.
- Authors
- Phalip V, Lemoine Y, Jeltsch JM
- Citation
- Curr Microbiol 1999 Dec;39(6):348-0350
- Publication year
- 1999
- Abstract
- A Saccharomyces cerevisiae mutant affected in the last step of the biotin biosynthesis pathway was isolated by using a transposon mutagenesis method. The gene BIO2, encoding a biotin synthase, is shown to be interrupted in this mutant. Heterologous complementation experiment allowed the cloning and the characterization of a novel bio gene: bio2, encoding biotin synthase from Schizosaccharomyces pombe.