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Reference - PMID:10525840 - Cloning of Schizosaccharomyces pombe bio2 by heterologous complementation of a Saccharomyces cerevisiae mutant.

Reference summary

PubMed ID
PMID:10525840
Title
Cloning of Schizosaccharomyces pombe bio2 by heterologous complementation of a Saccharomyces cerevisiae mutant.
Authors
Phalip V, Lemoine Y, Jeltsch JM
Citation
Curr Microbiol 1999 Dec;39(6):348-0350
Publication year
1999
Abstract
A Saccharomyces cerevisiae mutant affected in the last step of the biotin biosynthesis pathway was isolated by using a transposon mutagenesis method. The gene BIO2, encoding a biotin synthase, is shown to be interrupted in this mutant. Heterologous complementation experiment allowed the cloning and the characterization of a novel bio gene: bio2, encoding biotin synthase from Schizosaccharomyces pombe.

Annotation

GO biological process

GO:0009102 - biotin biosynthetic process

Genes:

GO molecular function

GO:0004076 - biotin synthase activity

Genes: