Reference - PMID:12565827 - Fission yeast synaptobrevin is involved in cytokinesis and cell elongation.
Reference summary
- PubMed ID
- PMID:12565827
- Title
- Fission yeast synaptobrevin is involved in cytokinesis and cell elongation.
- Authors
- Edamatsu M, Toyoshima YY
- Citation
- Biochem Biophys Res Commun 2003 Feb 14;301(3):641-5
- Publication year
- 2003
- Abstract
- Synaptobrevin is a vesicle-associated membrane protein playing an essential role in regulated vesicle transport. In this study, we characterized Syb1, synaptobrevin of Schizosaccharomyces pombe. Syb1 was located on various sizes of vesicle-like structures in the cytoplasm and enriched in the medial region and cell ends. Transport of Syb1 to the medial region was mainly dependent on F-actin and Myo52/Myo4. Syb1 is essential for cell viability and most of the syb1-null cells showed a round or short cylindrical form. These results suggest that Syb1 is involved in membrane trafficking of cytokinesis and cell elongation.
