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Reference - PMID:1318242 - Synthesis and degradation of polyphosphate in the fission yeast Schizosaccharomyces pombe: mutations in phosphatase genes do not affect polyphosphate metabolism.

Reference summary

PubMed ID
PMID:1318242
Title
Synthesis and degradation of polyphosphate in the fission yeast Schizosaccharomyces pombe: mutations in phosphatase genes do not affect polyphosphate metabolism.
Authors
Müller J, Westenberg B, Boller T, Wiemken A
Citation
FEMS Microbiol Lett 1992 Apr 15;71(2):151-6
Publication year
1992
Abstract
The fission yeast Schizosaccharomyces pombe was found to accumulate large amounts of polyphosphate, particularly when grown on arginine as the nitrogen source. Upon transfer to a medium without phosphate, polyphosphate was degraded and served as an endogenous phosphate reserve. When phosphate was added again after a prolonged period of phosphate starvation, fission yeast cells synthesized more polyphosphate than they had contained before starvation, a phenomenon known as over-compensation. Strains carrying mutated structural genes for three different phosphatases, pho1, pho2 or pho3, degraded polyphosphate at the same rate as the wild-type strain during phosphate starvation and showed the same type of over-compensation when phosphate was added again.

Annotation

Single locus phenotype

FYPO:0007154 - normal polyphosphate biosynthesis during cellular response to replete phosphate

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FYPO:0007153 - normal polyphosphate catabolism during cellular response to phosphate starvation

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