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Reference - PMID:14723223 - Sulphate metabolism of selenate-resistant Schizosaccharomyces pombe mutants.

Reference summary

PubMed ID
PMID:14723223
Title
Sulphate metabolism of selenate-resistant Schizosaccharomyces pombe mutants.
Authors
Bánszky L, Simonics T, Maráz A
Citation
J Gen Appl Microbiol 2003 Oct;49(5):271-8
Publication year
2003
Abstract
Selenate-resistant mutants were obtained from several strains of Schizosaccharomyces pombe. The obtained mutants all belonged to the same genetic complementation group. They were low in sulphate uptake activity and in ATP sulphurylase activity. They grew on medium containing sulphite, thiosulphate, cysteine or glutathione but not methionine as the sole source of sulphur. From these results, the mutants were concluded to carry mutations in the ATP sulphurylase gene. Inability of the mutants to utilize methionine as a sulphur source is rationalized by the absence of the reverse transsulphurylation pathway in this organism; wild type strains must utilize methionine as a sulphur source after it is degraded to give rise to sulphate.

Annotation

GO biological process

GO:0000103 - sulfate assimilation

Genes:

GO molecular function

GO:0004781 - sulfate adenylyltransferase (ATP) activity

Genes:

Single locus phenotype

FYPO:0002752 - abolished cell population growth on methionine sulfur source

Genes:

Genotypes:

FYPO:0002753 - abolished cell population growth on sulfate sulfur source

Genes:

Genotypes:

FYPO:0002751 - decreased sulfate import

Genes:

Genotypes:

FYPO:0000752 - resistance to selenate

Genes:

Genotypes: