Reference - PMID:17151234 - Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe.
Reference summary
- PubMed ID
- PMID:17151234
- Title
- Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe.
- Authors
- Cavero S, Chahwan C, Russell P
- Citation
- Genetics 2007 Feb;175(2):963-7
- Publication year
- 2007
- Abstract
- The accurate repair of DNA double-strand breaks is essential for cell survival and maintenance of genome integrity. Here we describe xlf1+, a gene in the fission yeast Schizosaccharomyces pombe that is required for repair of double-strand breaks by nonhomologous end joining during G1 phase of the cell cycle. Xlf1 is the ortholog of budding yeast Nej1 and human XLF/Cernunnos proteins.
