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Reference - PMID:1943699 - Thirty-three nucleotides of 5' flanking sequence including the 'TATA' box are necessary and sufficient for efficient U2 snRNA transcription in Schizosaccharomyces pombe.

Reference summary

PubMed ID
PMID:1943699
Title
Thirty-three nucleotides of 5' flanking sequence including the 'TATA' box are necessary and sufficient for efficient U2 snRNA transcription in Schizosaccharomyces pombe.
Authors
Dandekar T, Tollervey D
Citation
Mol Microbiol 1991 Jul;5(7):1621-5
Publication year
1991
Abstract
We have sequenced the 5' flanking region of the U2 gene and compared this with the 5' flanking sequences of other snRNA genes from Schizosaccharomyces pombe. This revealed no regions of clear homology 5' to a region surrounding the 'TATA' box at -32 to -29. Deletion analysis shows that a 5' flanking region extending to only -33 is sufficient for accurate and efficient transcription of U2 in Schizosaccharomyces pombe.

Annotation

Single locus phenotype

FYPO:0004204 - decreased mature snRNA level

Genes:

Genotypes:

FYPO:0003161 - RNA absent from cell during vegetative growth

Genes:

Genotypes: