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Reference - PMID:20537132 - Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Reference summary

PubMed ID
PMID:20537132
Title
Global fitness profiling of fission yeast deletion strains by barcode sequencing.
Authors
Han TX, Xu XY, Zhang MJ, Peng X, Du LL
Citation
Genome Biol 2010;11(6):R60
Publication year
2010
Abstract
A genome-wide deletion library is a powerful tool for probing gene functions and one has recently become available for the fission yeast Schizosaccharomyces pombe. Here we use deep sequencing to accurately characterize the barcode sequences in the deletion library, thus enabling the quantitative measurement of the fitness of fission yeast deletion strains by barcode sequencing.

Annotation

GO biological process

GO:0009085 - L-lysine biosynthetic process

Genes:

Single locus phenotype

FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

Genes:

Genotypes:

FYPO:0000039 - growth auxotrophic for lysine

Genes:

Genotypes:

FYPO:0001032 - resistance to camptothecin

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Genotypes:

FYPO:0000069 - resistance to thiabendazole

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Genotypes:

FYPO:0000085 - sensitive to camptothecin

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Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

Genes:

Genotypes:

FYPO:0000091 - sensitive to thiabendazole

Genes:

Genotypes:

FYPO:0000268 - sensitive to UV during vegetative growth

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Genotypes: