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Reference - PMID:22771993 - Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast.

Reference summary

PubMed ID
PMID:22771993
Title
Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast.
Authors
Cassart C, Drogat J, Migeot V, Hermand D
Citation
Transcription 2012;3(5):231-4
Publication year
2012
Abstract
The "CTD code" links the combinatorial potential of the modifications found on the Rpb1 C-terminal domain (CTD) to the growing group of CTD binding effectors. The genetic dissection of serine 2 and serine 7 function within the CTD in both budding and fission yeast reveals distinct in vivo requirement.

Annotation

Single locus phenotype

FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0000080 - decreased cell population growth at low temperature

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FYPO:0004461 - decreased level of regulation of sexual differentiation gene mRNA during nitrogen starvation

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FYPO:0000708 - decreased mating efficiency

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FYPO:0000674 - normal cell population growth at high temperature

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000107 - sensitive to latrunculin A

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