Reference - PMID:29467252 - Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables.
Reference summary
- PubMed ID
- PMID:29467252
- Title
- Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables.
- Authors
- Shin M, van Leeuwen J, Boone C, Bretscher A
- Citation
- Mol Biol Cell 2018 Apr 15;29(8):923-936
- Publication year
- 2018
- Abstract
- Yeast Aim21 is recruited by the SH3-containing proteins Bbc1 and Abp1 to patches and, with Tda2, reduces barbed end assembly to balance the distribution of actin between patches and cables. Aim21/Tda2 also interacts with Cap1/Cap2, revealing a complex interplay between actin assembly regulators.
