Reference - PMID:3481026 - Strains of Schizosaccharomyces pombe with a disrupted swi1 gene still show some mating-type switching.
Reference summary
- PubMed ID
- PMID:3481026
- Title
- Strains of Schizosaccharomyces pombe with a disrupted swi1 gene still show some mating-type switching.
- Authors
- Schmidt H
- Citation
- Mol Gen Genet 1987 Dec;210(3):485-9
- Publication year
- 1987
- Abstract
- The swi1+ gene is necessary for effective mating-type (MT) switching in Schizosaccharomyces pombe. It was cloned on a 4.2 kb genomic DNA fragment. By site-directed integration into the genome and gene disruption experiments it was proved that the swi1+ gene itself and not a suppressor had been isolated. Disruption of the swi1+ gene causes a phenotype identical to that of the original swi1 mutant, i.e. the strain still shows some MT switching. The swi1 gene is unique in the genome and gives rise to a 3 kb mRNA.
