Reference - PMID:38940614 - Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase.

GO:0052846 - inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

GO:0052847 - inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

GO:0052843 - inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

GO:0052845 - inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

FYPO:0005369 - abolished cell population growth at low temperature

Genes:

• aps1 (SPAC13G6.14)
• siw14 (SPBC17A3.03c)

Genotypes:

• aps1-E89A,E93A(aa) siw14delta
• aps1delta siw14delta

FYPO:0001575 - abolished vegetative cell population growth

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• seb1 (SPAC222.09)

Genotypes:

• aps1delta seb1-G476S(aa)
• asp1-H397A(aa) seb1-G476S(aa)

FYPO:0000082 - decreased cell population growth at high temperature

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1delta asp1-H397A(aa) tgp1delta
• aps1delta siw14delta
• aps1delta siw14delta tgp1delta

FYPO:0000080 - decreased cell population growth at low temperature

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1delta asp1-H397A(aa) tgp1delta

FYPO:0001355 - decreased vegetative cell population growth

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• seb1 (SPAC222.09)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1-E89A,E93A(aa) siw14delta
• aps1delta asp1-H397A(aa) tgp1delta
• aps1delta seb1-G476S(aa)
• aps1delta siw14delta

FYPO:0002243 - increased acid phosphatase activity

Genes:

• aps1 (SPAC13G6.14)
• siw14 (SPBC17A3.03c)

Genotypes:

• aps1-E89A,E93A(aa) siw14delta

FYPO:0000674 - normal cell population growth at high temperature

Genes:

• aps1 (SPAC13G6.14)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1delta tgp1delta
• siw14delta tgp1delta

FYPO:0001357 - normal vegetative cell population growth

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• seb1 (SPAC222.09)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1delta seb1-G476S(aa) tgp1delta
• aps1delta siw14delta tgp1delta
• aps1delta tgp1delta
• asp1-H397A(aa) seb1-G476S(aa)
• asp1-H397A(aa) seb1-G476S(aa) tgp1delta
• siw14delta tgp1delta

FYPO:0005485 - abolished inositol phosphate phosphatase activity

Genes:

• aps1 (SPAC13G6.14)

Genotypes:

• aps1-E89A,E93A(aa)[Overexpression]

FYPO:0008276 - abolished polyphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

Genotypes:

• aps1-E89A,E93A(aa)[Overexpression]

FYPO:0008281 - decreased cellular 1,5-IP8 level

Genes:

• asp1 (SPCC1672.06c)
• kcs1 (SPCC970.08)

Genotypes:

• asp1-D333A(aa)
• asp1delta
• kcs1-R332T(aa)

FYPO:0008283 - decreased cellular 1-IP7 level

Genes:

• asp1 (SPCC1672.06c)
• kcs1 (SPCC970.08)

Genotypes:

• asp1-D333A(aa)
• asp1delta
• kcs1-R332T(aa)

FYPO:0008282 - decreased cellular 5-IP7 level

Genes:

• kcs1 (SPCC970.08)

Genotypes:

• kcs1-R332T(aa)

FYPO:0002243 - increased acid phosphatase activity

Genes:

• aps1 (SPAC13G6.14)

Genotypes:

• aps1-E89A,E93A(aa)

FYPO:0008277 - increased cellular 1,5-IP8 level

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• siw14 (SPBC17A3.03c)

Genotypes:

• aps1delta
• asp1(1-385)(386-920 Δaa)
• asp1(1-492)(493-920 Δaa)
• asp1-H397A(aa)
• siw14delta

FYPO:0008279 - increased cellular 1-IP7 level

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)

Genotypes:

• aps1delta
• asp1(1-385)(386-920 Δaa)
• asp1(1-492)(493-920 Δaa)
• asp1-H397A(aa)

FYPO:0008278 - increased cellular 5-IP7 level

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• siw14 (SPBC17A3.03c)

Genotypes:

• aps1delta
• asp1-D333A(aa)
• asp1delta
• siw14delta

FYPO:0003267 - normal acid phosphatase activity

Genes:

• siw14 (SPBC17A3.03c)

Genotypes:

• siw14delta

FYPO:0000674 - normal cell population growth at high temperature

Genes:

• aps1 (SPAC13G6.14)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1delta
• siw14delta
• tgp1delta

FYPO:0008286 - normal cellular 1-IP7 level

Genes:

• siw14 (SPBC17A3.03c)

Genotypes:

• siw14delta

FYPO:0008285 - normal cellular 5-IP7 level

Genes:

• asp1 (SPCC1672.06c)

Genotypes:

• asp1(1-385)(386-920 Δaa)
• asp1(1-492)(493-920 Δaa)
• asp1-H397A(aa)

FYPO:0008275 - normal polyphosphatase activity

Genes:

• aps1 (SPAC13G6.14)

Genotypes:

• aps1-(11-210)(1-10 Δaa)
• aps1-(26-210)(1-25 Δaa)

FYPO:0001357 - normal vegetative cell population growth

Genes:

• aps1 (SPAC13G6.14)
• asp1 (SPCC1672.06c)
• seb1 (SPAC222.09)
• siw14 (SPBC17A3.03c)
• tgp1 (SPBC1271.09)

Genotypes:

• aps1-E89A,E93A(aa)
• aps1delta
• asp1-H397A(aa)
• seb1-G476S(aa)
• siw14delta
• tgp1delta