Reference - PMID:41684683 - The Schizosaccharomyces pombe Glycosyltransferase Gmh5 is a Functional Homologue of the α-1,6-Mannosyltransferase Mnn10 Crucial for N-Glycan Processing.
Reference summary
- PubMed ID
- PMID:41684683
- Title
- The Schizosaccharomyces pombe Glycosyltransferase Gmh5 is a Functional Homologue of the α-1,6-Mannosyltransferase Mnn10 Crucial for N-Glycan Processing.
- Authors
- Lommel M, Hutzler F, Siukstaite L, Wild K, Grbavac A, Sinning I, Strahl S
- Citation
- Food Technol Biotechnol 2026;64(1):39-52
- Publication year
- 2026
- Abstract
- This study provides the first functional characterization of Gmh5p as a mannosyltransferase of the GT34 family and demonstrates its role in N-glycan biosynthesis. Our findings expand the current understanding of the diversity and specificity of glycosyltransferases in eukaryotes and highlight their importance in cell wall biology.
