Reference - PMID:7903653 - Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe.
Reference summary
- PubMed ID
- PMID:7903653
- Title
- Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe.
- Authors
- Barel I, MacDonald DW
- Citation
- FEMS Microbiol Lett 1993 Nov 01;113(3):267-72
- Publication year
- 1993
- Abstract
- Among the glutamate-requiring strains of Schizosaccharomyces pombe previously described [1], glu2 and glu3 strains were both shown to lack NAD-specific isocitrate dehydrogenase. glu4 strains were shown to lack glutamine:2-oxoglutarate aminotransferase (GOGAT), and to be defective in ammonia assimilation. The regulation of GOGAT activity in wild-type cells was investigated and was consistent with GOGAT and glutamine synthetase being involved in ammonium assimilation, particularly under conditions of nitrogen limitation.
