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Reference - PMID:8619315 - Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.

Reference summary

PubMed ID
PMID:8619315
Title
Gcs1, a gene encoding gamma-glutamylcysteine synthetase in the fission yeast Schizosaccharomyces pombe.
Authors
Coblenz A, Wolf K
Citation
Yeast 1995 Sep 30;11(12):1171-7
Publication year
1995
Abstract
By complementation of a mutant resistant to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) we have identified the gcs1 gene, encoding a putative gamma-glutamylcysteine synthetase. The gene is possibly interrupted by two introns and has 49% identical and 80% similar amino acids compared with the homologous protein from rat. In comparison with the Saccharomyces cerevisiae homologue it possesses 41% identical and 74% similar amino acids.

Annotation

GO biological process

GO:0071276 - cellular response to cadmium ion

Genes:

GO:0006750 - glutathione biosynthetic process

Genes:

GO molecular function

GO:0004357 - glutamate-cysteine ligase activity

Genes: