Reference - PMID:8861202 - The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe.
Reference summary
- PubMed ID
- PMID:8861202
- Title
- The sxa2-dependent inactivation of the P-factor mating pheromone in the fission yeast Schizosaccharomyces pombe.
- Authors
- Ladds G, Rasmussen EM, Young T, Nielsen O, Davey J
- Citation
- Mol Microbiol 1996 Apr;20(1):35-42
- Publication year
- 1996
- Abstract
- Haploid cells of the fission yeast Schizosaccharomyces pombe exist in one of two mating types, referred to as M and P. Conjugation occurs between cells of opposite mating type and is controlled by the reciprocal action of diffusible pheromones. Loss of function of the sxa2 gene in M cells causes hypersensitivity to the P-factor mating pheromone and a reduction in mating efficiency. Here we demonstrate the secretion of an sxa2-dependent carboxypeptidase that inactivates P-factor by removal of the C-terminal leucine residue.
