id: gomodel:667dfe8d00001131
title: lysine biosynthetic process (GO:0009085)
taxon: NCBITaxon:4896
status: production
comments:
- 'lysine biosynthesis source pathway

  https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2020.546213/full

  '
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objects:
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  label: homocitrate synthase activity
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  label: lys4 Spom
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- id: GO:0019878
  label: lysine biosynthetic process via aminoadipic acid
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: GO:0003994
  label: aconitate hydratase activity
  type: gocam:Object
- id: PomBase:SPBP4H10.15
  label: aco2 Spom
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: CHEBI:36459
  label: homocitrate(1-)
  type: gocam:Object
- id: GO:0004409
  label: homoaconitate hydratase activity
  type: gocam:Object
- id: PomBase:SPAC343.16
  label: lys2 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58174
  label: but-1-ene-1,2,4-tricarboxylate
  type: gocam:Object
- id: GO:0047046
  label: homoisocitrate dehydrogenase activity
  type: gocam:Object
- id: PomBase:SPAC31G5.04
  label: lys12 Spom
  type: gocam:Object
- id: CHEBI:15404
  label: (-)-homoisocitrate(3-)
  type: gocam:Object
- id: CHEBI:57499
  label: 2-oxoadipate(2-)
  type: gocam:Object
- id: GO:0004043
  label: L-aminoadipate-semialdehyde dehydrogenase activity
  type: gocam:Object
- id: PomBase:SPAP7G5.04c
  label: lys1 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004755
  label: saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity
  type: gocam:Object
- id: PomBase:SPBC3B8.03
  label: lys9 Spom
  type: gocam:Object
- id: CHEBI:58672
  label: L-2-aminoadipate(1-)
  type: gocam:Object
- id: GO:0004754
  label: saccharopine dehydrogenase (NAD+, L-lysine-forming) activity
  type: gocam:Object
- id: PomBase:SPAC227.18
  label: lys3 Spom
  type: gocam:Object
- id: CHEBI:16927
  label: L-saccharopine
  type: gocam:Object
- id: CHEBI:32551
  label: L-lysinium(1+)
  type: gocam:Object
- id: CHEBI:58321
  label: L-allysine zwitterion
  type: gocam:Object
- id: CHEBI:29985
  label: L-glutamate(1-)
  type: gocam:Object
- id: CHEBI:16810
  label: 2-oxoglutarate(2-)
  type: gocam:Object
- id: GO:0047536
  label: 2-aminoadipate transaminase activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0022857
  label: transmembrane transporter activity
  type: gocam:Object
- id: GO:0170037
  label: export from the mitochondrion
  type: gocam:Object
- id: GO:0031966
  label: mitochondrial membrane
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0015189
  label: L-lysine transmembrane transporter activity
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0004824
  label: lysine-tRNA ligase activity
  type: gocam:Object
- id: PomBase:SPCC18.08
  label: msk1 Spom
  type: gocam:Object
- id: GO:0006430
  label: lysyl-tRNA aminoacylation
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0008897
  label: holo-[acyl-carrier-protein] synthase activity
  type: gocam:Object
- id: PomBase:SPAC17C9.02c
  label: lys7 Spom
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2025-04-09'
  provided_by:
  - http://www.pombase.org
