id: gomodel:678073a900002931
title: fatty acid biosynthetic process (GO:0006633)
taxon: NCBITaxon:4896
status: production
comments:
- 'Automated change 2025-04-24: GO:0004108 replaced by GO:0036440'
- SPAPB2B4.06 appears to be a mitochondrial paralogy of the4, but I couldn't find
  how fatty acids might be generated from fatty-acyl-[ACP]
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      with_objects:
      - SGD:S000001538
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-23'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-23'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002413
    downstream_activity: gomodel:678073a900002931/678073a900003895
objects:
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: GO:0005783
  label: endoplasmic reticulum
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0004742
  label: dihydrolipoyllysine-residue acetyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC794.07
  label: lat1 Spom
  type: gocam:Object
- id: GO:0006086
  label: pyruvate decarboxylation to acetyl-CoA
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:57387
  label: oleoyl-CoA(4-)
  type: gocam:Object
- id: CHEBI:7725
  label: octanoyl-[acyl-carrier protein]
  type: gocam:Object
- id: CHEBI:57384
  label: malonyl-CoA(5-)
  type: gocam:Object
- id: GO:0003989
  label: acetyl-CoA carboxylase activity
  type: gocam:Object
- id: PomBase:SPAC56E4.04c
  label: cut6 Spom
  type: gocam:Object
- id: GO:2001295
  label: malonyl-CoA biosynthetic process
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: PomBase:SPAC4A8.11c
  label: fas2 Spom
  type: gocam:Object
- id: CHEBI:57288
  label: acetyl-CoA(4-)
  type: gocam:Object
- id: GO:0004313
  label: '[acyl-carrier-protein] S-acetyltransferase activity'
  type: gocam:Object
- id: PomBase:SPAC926.09c
  label: fas1 Spom
  type: gocam:Object
- id: GO:0006633
  label: fatty acid biosynthetic process
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004314
  label: '[acyl-carrier-protein] S-malonyltransferase activity'
  type: gocam:Object
- id: PomBase:SPAC11G7.05c
  label: mct1 Spom
  type: gocam:Object
- id: GO:0000036
  label: acyl carrier activity
  type: gocam:Object
- id: PomBase:SPAC4H3.09
  label: SPAC4H3.09 Spom
  type: gocam:Object
- id: GO:0008897
  label: holo-[acyl-carrier-protein] synthase activity
  type: gocam:Object
- id: PomBase:SPAC3G9.17
  label: ppt2 Spom
  type: gocam:Object
- id: ECO:0000255
  label: match to sequence model evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0004315
  label: 3-oxoacyl-[acyl-carrier-protein] synthase activity
  type: gocam:Object
- id: PomBase:SPBC887.13c
  label: cem1 Spom
  type: gocam:Object
- id: GO:0004316
  label: 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
  type: gocam:Object
- id: PomBase:SPAC3G9.02
  label: oar2 Spom
  type: gocam:Object
- id: GO:0019171
  label: (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
  type: gocam:Object
- id: PomBase:SPBC1105.15c
  label: htd2 Spom
  type: gocam:Object
- id: GO:0141148
  label: enoyl-[acyl-carrier-protein] reductase (NADPH) activity
  type: gocam:Object
- id: PomBase:SPAC26F1.04c
  label: etr1 Spom
  type: gocam:Object
- id: GO:0004321
  label: fatty-acyl-CoA synthase activity
  type: gocam:Object
- id: GO:0005835
  label: fatty acid synthase complex
  type: gocam:Object
- id: GO:0047617
  label: fatty acyl-CoA hydrolase activity
  type: gocam:Object
- id: PomBase:SPBC31F10.02
  label: the13 Spom
  type: gocam:Object
- id: PomBase:SPBC26H8.11c
  label: the4 Spom
  type: gocam:Object
- id: GO:0009922
  label: fatty acid elongase activity
  type: gocam:Object
- id: PomBase:SPAC1639.01c
  label: elo1 Spom
  type: gocam:Object
- id: GO:0042761
  label: very long-chain fatty acid biosynthetic process
  type: gocam:Object
- id: GO:0005789
  label: endoplasmic reticulum membrane
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC1B2.03c
  label: elo2 Spom
  type: gocam:Object
- id: GO:0141040
  label: very-long-chain 3-oxoacyl-CoA reductase activity
  type: gocam:Object
- id: PomBase:SPAC4G9.15
  label: ifa38 Spom
  type: gocam:Object
- id: GO:0030497
  label: fatty acid elongation
  type: gocam:Object
- id: GO:0018812
  label: 3-hydroxyacyl-CoA dehydratase activity
  type: gocam:Object
- id: PomBase:SPBC19C2.15c
  label: phs1 Spom
  type: gocam:Object
- id: GO:0019166
  label: trans-2-enoyl-CoA reductase (NADPH) activity
  type: gocam:Object
- id: PomBase:SPBC646.07c
  label: tsc13 Spom
  type: gocam:Object
- id: GO:0004768
  label: stearoyl-CoA 9-desaturase activity
  type: gocam:Object
- id: PomBase:SPCC1281.06c
  label: ole1 Spom
  type: gocam:Object
- id: GO:0006636
  label: unsaturated fatty acid biosynthetic process
  type: gocam:Object
- id: CHEBI:57394
  label: stearoyl-CoA(4-)
  type: gocam:Object
- id: GO:0003878
  label: ATP citrate synthase activity
  type: gocam:Object
- id: PomBase:SPBC1703.07
  label: acl1 Spom
  type: gocam:Object
- id: PomBase:SPAC22A12.16
  label: acl2 Spom
  type: gocam:Object
- id: CHEBI:16947
  label: citrate(3-)
  type: gocam:Object
- id: GO:0036440
  label: citrate synthase activity
  type: gocam:Object
- id: PomBase:SPAC6C3.04
  label: cit1 Spom
  type: gocam:Object
- id: GO:0006099
  label: tricarboxylic acid cycle
  type: gocam:Object
- id: GO:0005371
  label: tricarboxylate secondary active transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPBC83.13
  label: yhm2 Spom
  type: gocam:Object
- id: GO:0006843
  label: mitochondrial citrate transmembrane transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: CHEBI:16452
  label: oxaloacetate(2-)
  type: gocam:Object
- id: CHEBI:57379
  label: palmitoyl-CoA(4-)
  type: gocam:Object
- id: CHEBI:7896
  label: hexadecanoate
  type: gocam:Object
- id: PomBase:SPAPB2B4.06
  label: SPAPB2B4.06 Spom
  type: gocam:Object
- id: GO:0006631
  label: fatty acid metabolic process
  type: gocam:Object
- id: GO:0036042
  label: long-chain fatty acyl-CoA binding
  type: gocam:Object
- id: PomBase:SPBC1539.06
  label: acb1 Spom
  type: gocam:Object
- id: CHEBI:57287
  label: coenzyme A(4-)
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  - https://orcid.org/0009-0003-9059-1333
  date: '2025-05-19'
  provided_by:
  - http://www.pombase.org
