id: gomodel:6796b94c00000009
title: phosphatidylserine biosynthetic process (GO:0006659), phosphatidylethanolamine
  biosynthetic process (GO:0006646) and phosphatidylcholine biosynthetic process (GO:0006656)
taxon: NCBITaxon:4896
status: production
comments:
- Ale1 ?
activities:
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    term: PomBase:SPBC16E9.18
  molecular_function:
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    term: GO:0006646
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    term: CHEBI:57262
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    term: CHEBI:64612
- id: gomodel:6796b94c00000009/6796b94c00000142
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    term: PomBase:SPAC22A12.10
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    term: GO:0006646
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    term: CHEBI:17815
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    term: CHEBI:16732
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    term: PomBase:SPBC337.16
  molecular_function:
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    term: GO:0006656
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    downstream_activity: gomodel:6796b94c00000009/6796b94c00000107
- id: gomodel:6796b94c00000009/6796b94c00000152
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000077597
      - UniProtKB:Q8IDM2
      - UniProtKB:Q99447
      - MGI:MGI:1915921
      - SGD:S000003239
      - TAIR:locus:2064123
      - RGD:619970
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC15E1.05c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004306
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000077597
      - UniProtKB:Q99447
      - SGD:S000003239
      - MGI:MGI:1915921
      - TAIR:locus:2064123
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: GO:0006646
  has_output:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000077597
      - UniProtKB:Q8IDM2
      - UniProtKB:Q99447
      - MGI:MGI:1915921
      - SGD:S000003239
      - TAIR:locus:2064123
      - RGD:619970
      provenances:
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    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16732
- id: gomodel:6796b94c00000009/6796b94c00000011
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:25318672
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:1324908
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC13A2.03
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004605
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000349519
      - RGD:621185
      - UniProtKB:Q57U32
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: GO:0005789
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:25318672
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:1324908
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: GO:0016024
  has_input:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:25318672
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:1324908
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:16337
  has_output:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:25318672
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:1324908
      provenances:
      - contributor:
        - https://orcid.org/0009-0003-9059-1333
        date: '2025-01-27'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-01-27'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:17962
objects:
- id: CHEBI:16337
  label: phosphatidic acid
  type: gocam:Object
- id: GO:0004605
  label: phosphatidate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC13A2.03
  label: bbl1 Spom
  type: gocam:Object
- id: GO:0016024
  label: CDP-diacylglycerol biosynthetic process
  type: gocam:Object
- id: GO:0005789
  label: endoplasmic reticulum membrane
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:17962
  label: CDP-diacylglycerol
  type: gocam:Object
- id: GO:0003882
  label: CDP-diacylglycerol-serine O-phosphatidyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC1442.12
  label: pps1 Spom
  type: gocam:Object
- id: GO:0006659
  label: phosphatidylserine biosynthetic process
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:57262
  label: 3-sn-phosphatidyl-L-serine(1-)
  type: gocam:Object
- id: GO:0004609
  label: phosphatidylserine decarboxylase activity
  type: gocam:Object
- id: PomBase:SPBC16E9.18
  label: psd1 Spom
  type: gocam:Object
- id: GO:0006646
  label: phosphatidylethanolamine biosynthetic process
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC25B8.03
  label: psd2 Spom
  type: gocam:Object
- id: PomBase:SPAC31G5.15
  label: psd3 Spom
  type: gocam:Object
- id: CHEBI:64612
  label: 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion
  type: gocam:Object
- id: GO:0004608
  label: phosphatidylethanolamine N-methyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC26H8.03
  label: cho2 Spom
  type: gocam:Object
- id: GO:0006656
  label: phosphatidylcholine biosynthetic process
  type: gocam:Object
- id: GO:0000773
  label: phosphatidyl-N-methylethanolamine N-methyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC337.16
  label: cho1 Spom
  type: gocam:Object
- id: CHEBI:57643
  label: 1,2-diacyl-sn-glycero-3-phosphocholine
  type: gocam:Object
- id: GO:0004142
  label: diacylglycerol cholinephosphotransferase activity
  type: gocam:Object
- id: PomBase:SPAC22A12.10
  label: ept1 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:16436
  label: CDP-choline
  type: gocam:Object
- id: CHEBI:17815
  label: 1,2-diacyl-sn-glycerol
  type: gocam:Object
- id: GO:0004105
  label: choline-phosphate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC1827.02c
  label: pcy1 Spom
  type: gocam:Object
- id: GO:0006657
  label: CDP-choline pathway
  type: gocam:Object
- id: GO:0004103
  label: choline kinase activity
  type: gocam:Object
- id: PomBase:SPAC13G7.12c
  label: eki1 Spom
  type: gocam:Object
- id: CHEBI:15354
  label: choline
  type: gocam:Object
- id: GO:0004307
  label: ethanolaminephosphotransferase activity
  type: gocam:Object
- id: CHEBI:16732
  label: CDP-ethanolamine
  type: gocam:Object
- id: GO:0004306
  label: ethanolamine-phosphate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC15E1.05c
  label: ect1 Spom
  type: gocam:Object
- id: GO:0004305
  label: ethanolamine kinase activity
  type: gocam:Object
- id: CHEBI:16000
  label: ethanolamine
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2025-04-09'
  provided_by:
  - http://www.pombase.org
