id: gomodel:6796b94c00006848
title: TORC1 signaling (GO:0038202)
taxon: NCBITaxon:4896
status: production
activities:
- id: gomodel:6796b94c00006848/67b1629100000349
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:39910760
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-17'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPCC70.12c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0030291
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:39910760
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-17'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:39910760
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-17'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:39910760
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
- id: gomodel:6796b94c00006848/6796b94c00006918
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0061700
    members:
    - PomBase:SPAC12G12.01c
    - PomBase:SPAC11E3.05
    - PomBase:SPAC15F9.02
    - PomBase:SPAC4F8.11
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0060089
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:33534698
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0005774
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006907
- id: gomodel:6796b94c00006848/6796b94c00006868
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0033596
    members:
    - PomBase:SPAC22F3.13
    - PomBase:SPAC630.13c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005096
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000353
      reference: PMID:12136010
      with_objects:
      - PomBase:SPAC630.13c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000389117
      - PomBase:SPAC22F3.13
      - FB:FBgn0026317
      - UniProtKB:Q92574
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0033596
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000389117
      - PomBase:SPAC22F3.13
      - FB:FBgn0026317
      - RGD:620124
      - UniProtKB:Q92574
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  has_input:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-02'
      provided_by:
      - http://www.pombase.org
    term: PR:000059629
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006859
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006859
- id: gomodel:6796b94c00006848/6796b94c00006859
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC428.16c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003924
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000316
      reference: PMID:17121544
      with_objects:
      - PomBase:SPBC216.07c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000269
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-25'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-25'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006877
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-25'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006877
- id: gomodel:6796b94c00006848/6796b94c00006896
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - ', PTN000136006'
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1990131
    members:
    - PomBase:SPCC777.05
    - PomBase:SPBC337.13c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0043539
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:29199950
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0000329
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:34805795
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - ', PTN000136006'
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
  - type: CausalAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - ', PTN000136006'
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
- id: gomodel:6796b94c00006848/6796b94c00006967
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1990877
    members:
    - PomBase:SPBC24C6.08c
    - PomBase:SPAC30C2.07
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005096
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0000329
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
- id: gomodel:6796b94c00006848/6796b94c00006877
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: PR:000059629
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0043539
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:16262791
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
- id: gomodel:6796b94c00006848/6796b94c00006934
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0071986
    members:
    - PomBase:SPBC1778.05c
    - PomBase:SPAC222.19
    - PomBase:SPAC23D3.16
    - PomBase:SPBC29A10.17
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005085
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0000329
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006877
- id: gomodel:6796b94c00006848/6796b94c00006956
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000316
      reference: PMID:22344254
      with_objects:
      - PomBase:SPBC337.13c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC23H4.14
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005085
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - SGD:S000002235
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000314
      reference: PMID:22344254
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000984773
      - SGD:S000002235
      - PomBase:SPAC23H4.14
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0000329
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:22344254
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904263
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
  - type: CausalAssociation
    evidence:
    - term: ECO:0000316
      reference: PMID:22344254
      with_objects:
      - PomBase:SPBC337.13c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000316
      reference: PMID:22344254
      with_objects:
      - PomBase:SPBC337.13c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
- id: gomodel:6796b94c00006848/67c10cc400000231
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC8E4.12c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0030291
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
- id: gomodel:6796b94c00006848/6796b94c00006907
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:29199950
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1990130
    members:
    - PomBase:SPAC23H3.03c
    - PomBase:SPBC1604.08c
    - PomBase:SPBC543.04
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0005096
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:29199950
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0000329
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:29199950
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000315
      reference: PMID:29199950
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006896
- id: gomodel:6796b94c00006848/6796b94c00006849
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:28671615
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0031931
    members:
    - PomBase:SPCC162.12
    - PomBase:SPAC57A7.11
    - PomBase:SPBC216.07c
    - PomBase:SPBP18G5.03
    - PomBase:SPBC21B10.05c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004674
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:22976295
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-02-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-02-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0038202
- id: gomodel:6796b94c00006848/67c10cc400000223
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBP35G2.16c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0030291
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    term: GO:1904262
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
  - type: CausalAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
  - type: CausalAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - PomBase:SPCC720.12c
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-03'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-03'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002630
    downstream_activity: gomodel:6796b94c00006848/6796b94c00006849
objects:
- id: GO:0030291
  label: protein serine/threonine kinase inhibitor activity
  type: gocam:Object
- id: PomBase:SPCC70.12c
  label: ecl1 Spom
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: GO:1904262
  label: negative regulation of TORC1 signaling
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: PR:000059629
  label: Rhb1/GTP Spom
  type: gocam:Object
- id: PomBase:SPBP35G2.16c
  label: ecl2 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC8E4.12c
  label: ecl3 Spom
  type: gocam:Object
- id: GO:0004674
  label: protein serine/threonine kinase activity
  type: gocam:Object
- id: GO:0031931
  label: TORC1 complex
  type: gocam:Object
- id: PomBase:SPBP18G5.03
  label: toc1 Spom
  type: gocam:Object
- id: PomBase:SPBC216.07c
  label: tor2 Spom
  type: gocam:Object
- id: PomBase:SPAC57A7.11
  label: mip1 Spom
  type: gocam:Object
- id: PomBase:SPCC162.12
  label: tco89 Spom
  type: gocam:Object
- id: PomBase:SPBC21B10.05c
  label: wat1 Spom
  type: gocam:Object
- id: GO:0038202
  label: TORC1 signaling
  type: gocam:Object
- id: GO:0003924
  label: GTPase activity
  type: gocam:Object
- id: PomBase:SPBC428.16c
  label: rhb1 Spom
  type: gocam:Object
- id: GO:1904263
  label: positive regulation of TORC1 signaling
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: GO:0005096
  label: GTPase activator activity
  type: gocam:Object
- id: GO:0033596
  label: TSC1-TSC2 complex
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000353
  label: physical interaction evidence used in manual assertion
  type: gocam:Object
- id: GO:0043539
  label: protein serine/threonine kinase activator activity
  type: gocam:Object
- id: PomBase:SPAC22F3.13
  label: tsc1 Spom
  type: gocam:Object
- id: PomBase:SPAC630.13c
  label: tsc2 Spom
  type: gocam:Object
- id: GO:1990131
  label: Gtr1-Gtr2 GTPase complex
  type: gocam:Object
- id: PomBase:SPBC337.13c
  label: gtr1 Spom
  type: gocam:Object
- id: PomBase:SPCC777.05
  label: gtr2 Spom
  type: gocam:Object
- id: GO:0000329
  label: fungal-type vacuole membrane
  type: gocam:Object
- id: GO:1990130
  label: GATOR1 complex
  type: gocam:Object
- id: PomBase:SPBC1604.08c
  label: imp1 Spom
  type: gocam:Object
- id: PomBase:SPAC23H3.03c
  label: npr2 Spom
  type: gocam:Object
- id: PomBase:SPBC543.04
  label: npr3 Spom
  type: gocam:Object
- id: GO:0060089
  label: molecular transducer activity
  type: gocam:Object
- id: GO:0061700
  label: GATOR2 complex
  type: gocam:Object
- id: PomBase:SPAC12G12.01c
  label: sea4 Spom
  type: gocam:Object
- id: PomBase:SPAC4F8.11
  label: sea2 Spom
  type: gocam:Object
- id: PomBase:SPAC15F9.02
  label: seh1 Spom
  type: gocam:Object
- id: PomBase:SPAC11E3.05
  label: sea3 Spom
  type: gocam:Object
- id: GO:0005774
  label: vacuolar membrane
  type: gocam:Object
- id: GO:0005085
  label: guanyl-nucleotide exchange factor activity
  type: gocam:Object
- id: GO:0071986
  label: Ragulator complex
  type: gocam:Object
- id: PomBase:SPBC29A10.17
  label: lam1 Spom
  type: gocam:Object
- id: PomBase:SPBC1778.05c
  label: lam2 Spom
  type: gocam:Object
- id: PomBase:SPAC222.19
  label: lam3 Spom
  type: gocam:Object
- id: PomBase:SPAC23D3.16
  label: lam4 Spom
  type: gocam:Object
- id: PomBase:SPAC23H4.14
  label: vam6 Spom
  type: gocam:Object
- id: GO:1990877
  label: FNIP-folliculin RagC/D GAP
  type: gocam:Object
- id: PomBase:SPBC24C6.08c
  label: bhd1 Spom
  type: gocam:Object
- id: PomBase:SPAC30C2.07
  label: fnp1 Spom
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2025-03-03'
  provided_by:
  - http://www.pombase.org
