id: gomodel:67c10cc400001799
title: protein lipoylation (GO:0009249)
taxon: NCBITaxon:4896
status: production
comments:
- This is all known targets
- 'could not joint to pathways because has input does not appear as an entity. '
activities:
- id: gomodel:67c10cc400001799/680ad14200000849
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000863675
      - TAIR:locus:2197818
      - MGI:MGI:1914414
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-26'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC4F10.05c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0033819
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000107370
      - TAIR:locus:2197818
      - UniProtKB:A6NK58
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-26'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0033819
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-26'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: GO:0009107
  has_input:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:78463
  has_output:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:64479
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:78809
- id: gomodel:67c10cc400001799/67c10cc400004972
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
      - SGD:S000005015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN002351721
      - UniProtKB:Q8IJJ4
      - UniProtKB:P10515
      - SGD:S000005015
      - TAIR:locus:2092070
      - RGD:619859
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPCC794.07
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004742
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000568044
      - MGI:MGI:2385311
      - SGD:S000003425
      - UniProtKB:P10515
      - RGD:619859
      - SGD:S000005015
      - ZFIN:ZDB-GENE-030131-2921
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0006086
- id: gomodel:67c10cc400001799/67c10cc400004952
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN008519424
      - UniProtKB:Q5B2R8
      - RGD:3286
      - RGD:620095
      - UniProtKB:P29803
      - SGD:S000000980
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC26F1.03
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004739
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN008519424
      - RGD:3286
      - UniProtKB:P08559
      - RGD:620095
      - SGD:S000000980
      - MGI:MGI:97532
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0006086
- id: gomodel:67c10cc400001799/67c10cc400004961
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000567956
      - SGD:S000002555
      - RGD:1359615
      - UniProtKB:Q9N0F1
      - UniProtKB:P36957
      - UniProtKB:P0AFG6
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC776.15c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004149
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000567957
      - TAIR:locus:2161670
      - UniProtKB:P36957
      - UniProtKB:Q8IEA6
      - SGD:S000002555
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000269
      reference: PMID:37164017
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000567956
      - PomBase:SPBC776.15c
      - UniProtKB:P0AFG6
      - UniProtKB:P36957
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0006099
- id: gomodel:67c10cc400001799/67c10cc400004983
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000111
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBP19A11.01
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0140104
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000036
      with_objects:
      - GO:0019464
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0005759
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN001711613
      - dictyBase:DDB_G0287773
      - RGD:619946
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    term: GO:0019464
- id: gomodel:67c10cc400001799/67c10cc400001800
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC17A3.09c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0016979
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN001757132
      - SGD:S000003582
      - MGI:MGI:3645211
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0016979
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0009249
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004983
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004961
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004952
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004972
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004961
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004972
  - type: CausalAssociation
    evidence:
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000255
      reference: GO_REF:0000050
      with_objects:
      - InterPro:IPR004562
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-16'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67c10cc400001799/67c10cc400004952
- id: gomodel:67c10cc400001799/67c10cc400001826
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000101947
      - UniProtKB:Q8IDQ0
      - TAIR:locus:2051384
      - MGI:MGI:1934604
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPBC8D2.15
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0016992
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000101947
      - MGI:MGI:1934604
      - TAIR:locus:2051384
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0005739
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000101947
      - UniProtKB:Q8IDQ0
      - TAIR:locus:2051384
      - MGI:MGI:1934604
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    term: GO:0009107
  has_input:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000101947
      - UniProtKB:Q8IDQ0
      - TAIR:locus:2051384
      - MGI:MGI:1934604
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-26'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-26'
      provided_by:
      - http://www.pombase.org
    term: CHEBI:78809
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000101947
      - UniProtKB:Q8IDQ0
      - TAIR:locus:2051384
      - MGI:MGI:1934604
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-03-07'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-03-07'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002413
    downstream_activity: gomodel:67c10cc400001799/67c10cc400001800
objects:
- id: GO:0016979
  label: lipoate-protein ligase activity
  type: gocam:Object
- id: PomBase:SPBC17A3.09c
  label: aim22 Spom
  type: gocam:Object
- id: GO:0009249
  label: protein lipoylation
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: ECO:0000255
  label: match to sequence model evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0016992
  label: lipoate synthase activity
  type: gocam:Object
- id: PomBase:SPBC8D2.15
  label: lip5 Spom
  type: gocam:Object
- id: GO:0009107
  label: lipoate biosynthetic process
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004739
  label: pyruvate dehydrogenase (acetyl-transferring) activity
  type: gocam:Object
- id: PomBase:SPAC26F1.03
  label: pda1 Spom
  type: gocam:Object
- id: GO:0006086
  label: pyruvate decarboxylation to acetyl-CoA
  type: gocam:Object
- id: GO:0004149
  label: dihydrolipoyllysine-residue succinyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC776.15c
  label: kgd2 Spom
  type: gocam:Object
- id: GO:0006099
  label: tricarboxylic acid cycle
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: GO:0004742
  label: dihydrolipoyllysine-residue acetyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC794.07
  label: lat1 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: GO:0140104
  label: molecular carrier activity
  type: gocam:Object
- id: PomBase:SPBP19A11.01
  label: gcv3 Spom
  type: gocam:Object
- id: GO:0019464
  label: glycine decarboxylation via glycine cleavage system
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: GO:0033819
  label: lipoyl(octanoyl) transferase activity
  type: gocam:Object
- id: PomBase:SPAC4F10.05c
  label: lip2 Spom
  type: gocam:Object
- id: CHEBI:78463
  label: O-(S-octanoylpantetheine-4-phosphoryl)serine(1-) residue
  type: gocam:Object
- id: CHEBI:78809
  label: N(6)-octanoyl-L-lysine residue
  type: gocam:Object
- id: CHEBI:64479
  label: O-(pantetheine-4'-phosphoryl)serine(1-) residue
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2025-04-26'
  provided_by:
  - http://www.pombase.org
